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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDRG1 All Species: 26.06
Human Site: Y112 Identified Species: 63.7
UniProt: Q92597 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92597 NP_001128714.1 394 42835 Y112 S F P A G Y M Y P S M D Q L A
Chimpanzee Pan troglodytes A5A6K6 357 39342 G101 G A P V F P L G Y Q Y P S L D
Rhesus Macaque Macaca mulatta XP_001088529 394 42883 Y112 S F P A G Y M Y P S M D Q L A
Dog Lupus familis XP_539170 384 41718 Y112 S F P V G Y M Y P S M D Q L A
Cat Felis silvestris
Mouse Mus musculus Q62433 394 42990 Y112 S F P V G Y M Y P S M D Q L A
Rat Rattus norvegicus Q6JE36 394 42936 Y112 S F P V G Y M Y P S M D Q L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418430 402 44200 Y112 S F Q A G Y I Y P S M D Q L A
Frog Xenopus laevis Q7ZWV3 396 43486 Y113 S F P A G Y M Y P S M D Q L A
Zebra Danio Brachydanio rerio Q5PR98 368 40449 Q105 V H I D A P G Q E E G A A V Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O02485 325 35573 H69 K E K A I F L H V C V P G Q E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.5 99.2 94.1 N.A. 93.6 93.4 N.A. N.A. 81.8 74.7 51.5 N.A. N.A. N.A. 25.1 N.A.
Protein Similarity: 100 69.5 99.4 95.9 N.A. 97.2 97.2 N.A. N.A. 90.8 86.1 69 N.A. N.A. N.A. 44.1 N.A.
P-Site Identity: 100 13.3 100 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 100 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 20 100 93.3 N.A. 93.3 93.3 N.A. N.A. 93.3 100 6.6 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 50 10 0 0 0 0 0 0 10 10 0 70 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 70 0 0 10 % D
% Glu: 0 10 0 0 0 0 0 0 10 10 0 0 0 0 10 % E
% Phe: 0 70 0 0 10 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 70 0 10 10 0 0 10 0 10 0 0 % G
% His: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 10 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 20 0 0 0 0 0 0 80 0 % L
% Met: 0 0 0 0 0 0 60 0 0 0 70 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 70 0 0 20 0 0 70 0 0 20 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 10 0 10 0 0 70 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 70 0 0 0 0 0 0 0 0 70 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 40 0 0 0 0 10 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 70 0 70 10 0 10 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _