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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
34.55
Human Site:
S281
Identified Species:
54.29
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
S281
K
K
L
M
S
S
N
S
T
D
L
P
L
N
I
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
S514
K
K
L
M
S
S
N
S
T
D
L
P
L
N
I
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
A281
K
K
L
M
S
A
N
A
S
D
L
P
L
S
I
Dog
Lupus familis
XP_534515
1048
117305
S470
K
K
L
M
S
S
N
S
T
D
L
P
L
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
S281
K
K
L
M
S
S
N
S
T
D
L
P
L
N
I
Rat
Rattus norvegicus
Q66HA8
858
96400
S281
K
K
L
M
S
S
N
S
T
D
L
P
L
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
S281
K
K
L
M
S
S
N
S
M
D
L
P
L
N
I
Chicken
Gallus gallus
NP_001153170
856
96066
S281
K
K
L
M
S
S
N
S
T
D
I
P
L
N
I
Frog
Xenopus laevis
P02827
647
70897
G163
R
Q
A
T
K
D
A
G
V
L
A
G
L
N
I
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
S281
K
K
L
M
S
A
N
S
S
D
L
P
L
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
D157
S
Q
R
Q
A
T
K
D
A
G
H
I
A
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
Q283
K
K
Q
M
S
A
N
Q
T
P
I
P
L
N
I
Sea Urchin
Strong. purpuratus
Q06068
889
98600
A281
K
K
L
M
S
A
N
A
T
L
I
S
M
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
S208
F
V
D
I
G
H
S
S
Y
T
C
S
I
M
A
Red Bread Mold
Neurospora crassa
O74225
707
78655
S223
K
G
E
L
S
V
K
S
T
A
C
D
R
H
F
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
73.3
100
N.A.
100
100
N.A.
93.3
93.3
20
86.6
N.A.
0
N.A.
66.6
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
33.3
100
N.A.
26.6
N.A.
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
27
7
14
7
7
7
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% C
% Asp:
0
0
7
0
0
7
0
7
0
60
0
7
0
0
0
% D
% Glu:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
7
0
0
7
0
0
7
0
7
0
7
0
7
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
7
0
0
7
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
20
7
7
0
80
% I
% Lys:
80
74
0
0
7
0
14
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
67
7
0
0
0
0
0
14
54
0
74
0
7
% L
% Met:
0
0
0
74
0
0
0
0
7
0
0
0
7
7
0
% M
% Asn:
0
0
0
0
0
0
74
0
0
0
0
0
0
74
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
67
0
0
0
% P
% Gln:
0
14
7
7
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
7
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
7
0
0
0
80
47
7
67
14
0
0
14
0
7
0
% S
% Thr:
0
0
0
7
0
7
0
0
60
7
0
0
0
0
0
% T
% Val:
0
7
0
0
0
7
0
0
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _