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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPH1 All Species: 26.97
Human Site: S554 Identified Species: 42.38
UniProt: Q92598 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92598 NP_006635.2 858 96865 S554 D A Q Q T S Q S P P S P E L T
Chimpanzee Pan troglodytes XP_001142849 1091 122133 S787 D A Q Q T S Q S P P S P E L T
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 A554 E E M E T S Q A G S K D K K M
Dog Lupus familis XP_534515 1048 117305 S744 D G Q Q T S Q S P P S P E L T
Cat Felis silvestris
Mouse Mus musculus Q61699 858 96389 S555 D G Q Q T S Q S P P S P E L T
Rat Rattus norvegicus Q66HA8 858 96400 S555 D G Q Q T S Q S P P S P E L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509055 859 95987 S555 D D H Q T P Q S P P P P E P P
Chicken Gallus gallus NP_001153170 856 96066 S554 D G Q Q T S Q S P P S S E P P
Frog Xenopus laevis P02827 647 70897 T423 K R N T T I P T K Q T Q S F T
Zebra Danio Brachydanio rerio NP_956151 840 94728 E560 S A E E G K Q E K K S D Q P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VG58 641 70235 R417 K L I E R N C R I P C K Q T K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 D552 E S I P V S Y D V Q K F H N L
Sea Urchin Strong. purpuratus Q06068 889 98600 S574 S K D Q T S E S S K S D K E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32589 693 77348 Q468 N W E I T G V Q L P E G Q D S
Red Bread Mold Neurospora crassa O74225 707 78655 K483 D F M I C K L K A R I N I H G
Conservation
Percent
Protein Identity: 100 78.6 63.5 76.9 N.A. 93.4 92.4 N.A. 84.7 81.4 28.5 61.7 N.A. 27 N.A. 42 51.1
Protein Similarity: 100 78.6 77.9 79.6 N.A. 96.8 96.6 N.A. 92.5 90.7 45.7 77.3 N.A. 45.9 N.A. 58.9 67.9
P-Site Identity: 100 100 20 93.3 N.A. 93.3 93.3 N.A. 60 73.3 13.3 20 N.A. 6.6 N.A. 6.6 33.3
P-Site Similarity: 100 100 46.6 93.3 N.A. 93.3 93.3 N.A. 60 73.3 26.6 40 N.A. 26.6 N.A. 20 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.5 36.3
Protein Similarity: N.A. N.A. N.A. N.A. 51 53
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 40 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 0 0 0 7 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 7 0 7 0 0 0 7 0 0 0 0 % C
% Asp: 54 7 7 0 0 0 0 7 0 0 0 20 0 7 0 % D
% Glu: 14 7 14 20 0 0 7 7 0 0 7 0 47 7 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 0 7 0 7 0 % F
% Gly: 0 27 0 0 7 7 0 0 7 0 0 7 0 0 7 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 7 7 0 % H
% Ile: 0 0 14 14 0 7 0 0 7 0 7 0 7 0 0 % I
% Lys: 14 7 0 0 0 14 0 7 14 14 14 7 14 7 7 % K
% Leu: 0 7 0 0 0 0 7 0 7 0 0 0 0 34 7 % L
% Met: 0 0 14 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 7 0 7 0 0 7 0 0 0 0 0 7 0 7 0 % N
% Pro: 0 0 0 7 0 7 7 0 47 60 7 40 0 20 20 % P
% Gln: 0 0 40 54 0 0 60 7 0 14 0 7 20 0 0 % Q
% Arg: 0 7 0 0 7 0 0 7 0 7 0 0 0 0 0 % R
% Ser: 14 7 0 0 0 60 0 54 7 7 54 7 7 0 14 % S
% Thr: 0 0 0 7 74 0 0 7 0 0 7 0 0 7 40 % T
% Val: 0 0 0 0 7 0 7 0 7 0 0 0 0 0 0 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _