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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
27.88
Human Site:
T700
Identified Species:
43.81
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
T700
E
E
L
M
K
I
G
T
P
V
K
V
R
F
Q
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
T933
E
E
L
M
K
I
G
T
P
V
K
V
R
F
Q
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
Q683
A
E
L
K
N
L
G
Q
P
I
K
I
R
F
Q
Dog
Lupus familis
XP_534515
1048
117305
T890
E
E
L
M
K
I
G
T
P
V
K
V
R
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
T701
E
E
L
M
K
M
G
T
P
V
K
V
R
F
Q
Rat
Rattus norvegicus
Q66HA8
858
96400
T701
E
E
L
M
K
M
G
T
P
V
K
V
R
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
T701
D
E
L
T
K
L
G
T
P
I
K
I
R
C
Q
Chicken
Gallus gallus
NP_001153170
856
96066
T700
E
D
L
K
K
L
G
T
P
I
E
M
R
Y
Q
Frog
Xenopus laevis
P02827
647
70897
Q521
E
D
I
E
K
M
V
Q
E
A
E
K
Y
K
A
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
Q685
A
E
L
K
N
L
G
Q
P
I
Q
D
R
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
R515
L
S
Q
A
E
I
D
R
M
V
N
E
A
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
E650
P
V
V
E
R
Y
R
E
S
E
T
R
K
P
A
Sea Urchin
Strong. purpuratus
Q06068
889
98600
D718
N
S
L
K
K
I
G
D
P
V
E
N
R
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
E566
A
Q
D
K
L
V
A
E
T
E
D
R
K
N
T
Red Bread Mold
Neurospora crassa
O74225
707
78655
Y581
K
K
N
E
L
E
T
Y
I
Y
D
L
R
N
K
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
53.3
100
N.A.
93.3
93.3
N.A.
60
53.3
13.3
33.3
N.A.
13.3
N.A.
0
53.3
P-Site Similarity:
100
100
73.3
100
N.A.
100
100
N.A.
86.6
93.3
40
66.6
N.A.
26.6
N.A.
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
7
0
0
7
0
0
7
0
0
7
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
14
7
0
0
0
7
7
0
0
14
7
0
0
0
% D
% Glu:
47
54
0
20
7
7
0
14
7
14
20
7
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
0
% F
% Gly:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
34
0
0
7
27
0
14
0
0
0
% I
% Lys:
7
7
0
34
60
0
0
0
0
0
47
7
14
7
20
% K
% Leu:
7
0
67
0
14
27
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
34
0
20
0
0
7
0
0
7
0
0
0
% M
% Asn:
7
0
7
0
14
0
0
0
0
0
7
7
0
14
0
% N
% Pro:
7
0
0
0
0
0
0
0
67
0
0
0
0
7
0
% P
% Gln:
0
7
7
0
0
0
0
20
0
0
7
0
0
0
54
% Q
% Arg:
0
0
0
0
7
0
7
7
0
0
0
14
74
0
7
% R
% Ser:
0
14
0
0
0
0
0
0
7
0
0
0
0
0
0
% S
% Thr:
0
0
0
7
0
0
7
47
7
0
7
0
0
0
7
% T
% Val:
0
7
7
0
0
7
7
0
0
47
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
7
0
7
0
0
7
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _