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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT8
All Species:
3.94
Human Site:
S431
Identified Species:
8.67
UniProt:
Q92599
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92599
NP_001092281.1
483
55756
S431
D
K
D
K
K
N
R
S
D
I
G
A
H
Q
P
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
H380
E
A
E
L
Q
R
R
H
E
Q
M
K
K
N
L
Rhesus Macaque
Macaca mulatta
XP_001104760
440
50856
L389
V
E
E
K
R
R
E
L
E
E
E
T
N
A
F
Dog
Lupus familis
XP_531903
531
61013
S479
D
K
D
K
K
N
R
S
D
I
G
V
H
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHH9
429
49794
I376
K
F
E
H
L
K
R
I
H
Q
E
E
K
R
K
Rat
Rattus norvegicus
B0BNF1
442
51234
L391
V
E
E
K
R
R
E
L
E
E
E
T
N
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510590
457
52831
L406
V
E
E
K
R
R
E
L
E
E
E
M
N
A
F
Chicken
Gallus gallus
Q5ZMH1
349
40206
F298
Q
D
L
H
Y
E
N
F
R
S
E
R
L
K
R
Frog
Xenopus laevis
Q6AXA6
427
49720
Q376
M
Q
L
K
R
I
H
Q
E
E
S
K
K
V
E
Zebra Danio
Brachydanio rerio
Q642H3
420
48980
E369
R
E
L
H
E
K
F
E
Q
L
K
R
M
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54359
419
48456
K368
S
E
K
D
L
H
A
K
F
E
K
L
K
R
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.8
89.4
89
N.A.
87.1
88.1
N.A.
82.6
28.7
77.8
77.4
N.A.
59.6
N.A.
N.A.
N.A.
Protein Similarity:
100
56.7
89.8
90
N.A.
87.9
89.4
N.A.
86.3
47.6
84
81.9
N.A.
71.4
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
86.6
N.A.
6.6
6.6
N.A.
6.6
0
6.6
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
40
86.6
N.A.
20
40
N.A.
40
6.6
26.6
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
10
0
0
0
0
10
0
28
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
10
19
10
0
0
0
0
19
0
0
0
0
0
10
% D
% Glu:
10
46
46
0
10
10
28
10
46
46
46
10
0
0
10
% E
% Phe:
0
10
0
0
0
0
10
10
10
0
0
0
0
0
28
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% G
% His:
0
0
0
28
0
10
10
10
10
0
0
0
19
10
0
% H
% Ile:
0
0
0
0
0
10
0
10
0
19
0
0
0
0
0
% I
% Lys:
10
19
10
55
19
19
0
10
0
0
19
19
37
10
10
% K
% Leu:
0
0
28
10
19
0
0
28
0
10
0
10
10
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
10
10
10
0
0
% M
% Asn:
0
0
0
0
0
19
10
0
0
0
0
0
28
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
10
10
0
0
10
0
0
10
10
19
0
0
0
19
10
% Q
% Arg:
10
0
0
0
37
37
37
0
10
0
0
19
0
19
10
% R
% Ser:
10
0
0
0
0
0
0
19
0
10
10
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% T
% Val:
28
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _