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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOCK2
All Species:
30
Human Site:
S1724
Identified Species:
66
UniProt:
Q92608
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92608
NP_004937.1
1830
211948
S1724
E
S
D
L
K
R
L
S
R
K
H
E
F
M
S
Chimpanzee
Pan troglodytes
XP_527109
1830
211979
S1724
E
S
D
L
K
R
L
S
R
K
H
E
F
M
S
Rhesus Macaque
Macaca mulatta
XP_001107224
1870
215340
T1758
E
P
D
L
M
S
P
T
R
K
A
Q
R
P
K
Dog
Lupus familis
XP_546246
1849
214187
S1733
E
S
D
L
K
R
L
S
R
K
H
E
F
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C3J5
1828
211715
S1722
E
S
D
L
K
R
L
S
R
K
Q
E
F
M
S
Rat
Rattus norvegicus
XP_001068649
1831
211708
S1725
E
S
E
L
K
R
L
S
R
K
H
E
F
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508993
1829
212107
S1719
E
S
D
L
K
R
L
S
R
K
H
E
F
M
S
Chicken
Gallus gallus
XP_425184
1893
219602
S1705
I
S
D
M
K
C
L
S
R
K
Y
E
F
M
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103481
1866
215254
E1722
D
I
P
L
Q
A
N
E
A
V
I
L
S
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477144
1970
226442
S1858
F
P
D
T
R
S
L
S
E
S
S
N
R
N
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785550
1874
216318
Q1762
K
A
N
H
V
P
M
Q
R
P
I
R
A
M
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
54.2
94.7
N.A.
95
94
N.A.
90.9
81.9
N.A.
57.9
N.A.
37.9
N.A.
N.A.
45.3
Protein Similarity:
100
99.5
70.2
96.8
N.A.
97.4
97
N.A.
94.9
87.8
N.A.
73.5
N.A.
57.9
N.A.
N.A.
63.7
P-Site Identity:
100
100
33.3
100
N.A.
93.3
93.3
N.A.
100
73.3
N.A.
6.6
N.A.
26.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
46.6
100
N.A.
93.3
100
N.A.
100
86.6
N.A.
26.6
N.A.
33.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
10
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
73
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
64
0
10
0
0
0
0
10
10
0
0
64
0
10
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
64
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
46
0
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
19
0
0
0
0
% I
% Lys:
10
0
0
0
64
0
0
0
0
73
0
0
0
0
10
% K
% Leu:
0
0
0
73
0
0
73
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
10
10
0
10
0
0
0
0
0
0
73
0
% M
% Asn:
0
0
10
0
0
0
10
0
0
0
0
10
0
10
0
% N
% Pro:
0
19
10
0
0
10
10
0
0
10
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
10
10
0
0
0
% Q
% Arg:
0
0
0
0
10
55
0
0
82
0
0
10
19
0
0
% R
% Ser:
0
64
0
0
0
19
0
73
0
10
10
0
10
0
73
% S
% Thr:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
19
% T
% Val:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _