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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOCK2
All Species:
24.85
Human Site:
S588
Identified Species:
54.67
UniProt:
Q92608
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92608
NP_004937.1
1830
211948
S588
T
L
S
R
S
S
S
S
V
G
G
L
S
V
S
Chimpanzee
Pan troglodytes
XP_527109
1830
211979
S588
T
L
S
R
S
S
S
S
V
G
G
L
S
V
S
Rhesus Macaque
Macaca mulatta
XP_001107224
1870
215340
T608
Q
A
S
K
N
L
V
T
F
T
P
S
K
D
N
Dog
Lupus familis
XP_546246
1849
214187
S597
T
L
S
R
S
S
S
S
V
G
G
L
S
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C3J5
1828
211715
S588
T
L
S
R
S
S
S
S
V
G
G
L
S
V
S
Rat
Rattus norvegicus
XP_001068649
1831
211708
S588
T
L
S
R
S
S
S
S
V
G
G
L
S
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508993
1829
212107
S582
T
L
S
R
S
S
S
S
I
G
G
L
S
A
S
Chicken
Gallus gallus
XP_425184
1893
219602
I568
T
L
G
R
N
S
S
I
V
G
G
L
S
V
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103481
1866
215254
N589
S
S
G
K
N
A
Q
N
L
G
S
F
T
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477144
1970
226442
T609
K
P
S
I
G
G
L
T
L
L
P
K
D
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785550
1874
216318
A594
E
D
K
P
Q
T
H
A
S
G
H
Q
K
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
54.2
94.7
N.A.
95
94
N.A.
90.9
81.9
N.A.
57.9
N.A.
37.9
N.A.
N.A.
45.3
Protein Similarity:
100
99.5
70.2
96.8
N.A.
97.4
97
N.A.
94.9
87.8
N.A.
73.5
N.A.
57.9
N.A.
N.A.
63.7
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
86.6
80
N.A.
13.3
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
66.6
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
10
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
10
10
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% F
% Gly:
0
0
19
0
10
10
0
0
0
82
64
0
0
10
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
10
10
0
0
0
0
10
0
% I
% Lys:
10
0
10
19
0
0
0
0
0
0
0
10
19
0
0
% K
% Leu:
0
64
0
0
0
10
10
0
19
10
0
64
0
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
28
0
0
10
0
0
0
0
0
0
10
% N
% Pro:
0
10
0
10
0
0
0
0
0
0
19
0
0
0
0
% P
% Gln:
10
0
0
0
10
0
10
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
64
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
73
0
55
64
64
55
10
0
10
10
64
0
73
% S
% Thr:
64
0
0
0
0
10
0
19
0
10
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
10
0
55
0
0
0
0
55
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _