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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHF16
All Species:
26.67
Human Site:
S490
Identified Species:
58.67
UniProt:
Q92613
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92613
NP_001070913.1
823
93808
S490
R
N
L
C
Y
M
I
S
R
R
E
K
L
K
L
Chimpanzee
Pan troglodytes
XP_001158286
830
94095
T498
R
N
L
T
Y
M
V
T
R
R
E
K
I
K
R
Rhesus Macaque
Macaca mulatta
XP_001100171
938
105923
S605
R
N
L
C
Y
M
I
S
R
R
E
K
L
K
L
Dog
Lupus familis
XP_538010
823
93327
S490
R
N
L
C
Y
M
I
S
R
R
E
K
L
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6IE82
823
93436
S490
R
N
L
C
Y
M
I
S
R
R
E
K
L
K
L
Rat
Rattus norvegicus
XP_001056752
824
93344
S491
R
N
L
C
Y
M
I
S
R
R
E
K
L
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416870
790
89532
S461
R
N
L
C
Y
M
V
S
R
R
E
K
L
K
L
Frog
Xenopus laevis
Q6GQJ2
827
94374
Q494
Q
L
F
T
H
L
R
Q
D
L
E
R
V
R
N
Zebra Danio
Brachydanio rerio
Q7ZVP1
795
89026
Q474
R
M
F
M
H
L
R
Q
D
L
E
R
V
R
N
Tiger Blowfish
Takifugu rubipres
NP_001041504
790
88254
H464
Q
P
Q
E
D
S
I
H
T
R
M
R
M
F
M
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20318
1042
117625
A610
S
T
P
I
L
E
I
A
E
K
E
E
V
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.5
86.7
89.3
N.A.
82
82.8
N.A.
N.A.
70.9
45.2
60
59.3
N.A.
N.A.
20.5
N.A.
Protein Similarity:
100
59.4
87.3
94.4
N.A.
89.1
90
N.A.
N.A.
83.2
61.4
73.2
73.2
N.A.
N.A.
35.9
N.A.
P-Site Identity:
100
66.6
100
100
N.A.
100
100
N.A.
N.A.
93.3
6.6
13.3
13.3
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
100
46.6
46.6
40
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
55
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
19
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
10
0
0
10
0
91
10
0
10
0
% E
% Phe:
0
0
19
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
19
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
64
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
64
0
64
0
% K
% Leu:
0
10
64
0
10
19
0
0
0
19
0
0
55
0
55
% L
% Met:
0
10
0
10
0
64
0
0
0
0
10
0
10
0
10
% M
% Asn:
0
64
0
0
0
0
0
0
0
0
0
0
0
0
19
% N
% Pro:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
19
0
10
0
0
0
0
19
0
0
0
0
0
0
0
% Q
% Arg:
73
0
0
0
0
0
19
0
64
73
0
28
0
19
19
% R
% Ser:
10
0
0
0
0
10
0
55
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
19
0
0
0
10
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
19
0
0
0
0
0
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _