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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHF16 All Species: 5.15
Human Site: S572 Identified Species: 11.33
UniProt: Q92613 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92613 NP_001070913.1 823 93808 S572 H S P D S S S S V H S I R N M
Chimpanzee Pan troglodytes XP_001158286 830 94095 S578 M G T S L V H S L K K P H K R
Rhesus Macaque Macaca mulatta XP_001100171 938 105923 S687 H S P D S S S S V H S I R S M
Dog Lupus familis XP_538010 823 93327 P572 P S P A S S S P V H G V R S M
Cat Felis silvestris
Mouse Mus musculus Q6IE82 823 93436 P572 S S P G S S S P G H S K R S P
Rat Rattus norvegicus XP_001056752 824 93344 P573 S S P G S S S P S H S K R S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416870 790 89532 D539 G N R P L S P D N N S T V Y S
Frog Xenopus laevis Q6GQJ2 827 94374 F568 D L K W H S A F F R K R L G S
Zebra Danio Brachydanio rerio Q7ZVP1 795 89026 K544 T L K L K M P K V Q L G N G K
Tiger Blowfish Takifugu rubipres NP_001041504 790 88254 K540 P A P R I T L K L K M P K S S
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20318 1042 117625 P751 S D A D V S S P K S S W L G S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.5 86.7 89.3 N.A. 82 82.8 N.A. N.A. 70.9 45.2 60 59.3 N.A. N.A. 20.5 N.A.
Protein Similarity: 100 59.4 87.3 94.4 N.A. 89.1 90 N.A. N.A. 83.2 61.4 73.2 73.2 N.A. N.A. 35.9 N.A.
P-Site Identity: 100 6.6 93.3 60 N.A. 53.3 53.3 N.A. N.A. 13.3 6.6 6.6 6.6 N.A. N.A. 26.6 N.A.
P-Site Similarity: 100 13.3 100 73.3 N.A. 60 60 N.A. N.A. 26.6 13.3 6.6 40 N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 0 0 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 28 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % F
% Gly: 10 10 0 19 0 0 0 0 10 0 10 10 0 28 0 % G
% His: 19 0 0 0 10 0 10 0 0 46 0 0 10 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 19 0 0 0 % I
% Lys: 0 0 19 0 10 0 0 19 10 19 19 19 10 10 10 % K
% Leu: 0 19 0 10 19 0 10 0 19 0 10 0 19 0 0 % L
% Met: 10 0 0 0 0 10 0 0 0 0 10 0 0 0 28 % M
% Asn: 0 10 0 0 0 0 0 0 10 10 0 0 10 10 0 % N
% Pro: 19 0 55 10 0 0 19 37 0 0 0 19 0 0 19 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 10 10 0 0 0 0 0 10 0 10 46 0 10 % R
% Ser: 28 46 0 10 46 73 55 28 10 10 55 0 0 46 37 % S
% Thr: 10 0 10 0 0 10 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 0 0 10 10 0 0 37 0 0 10 10 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _