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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GCN1L1 All Species: 17.88
Human Site: T2086 Identified Species: 49.17
UniProt: Q92616 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92616 NP_006827.1 2671 292744 T2086 Y L V P K L T T P P V N T R V
Chimpanzee Pan troglodytes XP_001159608 2671 292720 T2086 Y L V P K L T T P P V N T R V
Rhesus Macaque Macaca mulatta XP_001087027 2601 285392 T2016 Y L V P K L T T P P V N T R V
Dog Lupus familis XP_534701 2671 292720 T2086 Y L V P K L T T P P V N T R V
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510404 1592 172883 P1074 A G R T V Q P P D R V P R G R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663103 2281 249882 A1764 S T D T R K M A A Q I I G N M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392968 2646 293858 T2060 Y L V P Q L T T P P V N T K A
Nematode Worm Caenorhab. elegans NP_497506 2680 294946 K2103 Y L L P K L T K P P V N V H A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P33892 2672 296680 A2032 I L I P T L L A P P I D A F R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 94.7 96.7 N.A. N.A. N.A. N.A. 47.1 N.A. N.A. 58.4 N.A. N.A. 50.2 33 N.A.
Protein Similarity: 100 99.7 95.7 98.3 N.A. N.A. N.A. N.A. 50.8 N.A. N.A. 66.8 N.A. N.A. 68.4 54.4 N.A.
P-Site Identity: 100 100 100 100 N.A. N.A. N.A. N.A. 6.6 N.A. N.A. 0 N.A. N.A. 80 66.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. N.A. N.A. N.A. 6.6 N.A. N.A. 20 N.A. N.A. 93.3 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 0 0 23 12 0 0 0 12 0 23 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 0 0 0 0 12 0 0 12 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % F
% Gly: 0 12 0 0 0 0 0 0 0 0 0 0 12 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % H
% Ile: 12 0 12 0 0 0 0 0 0 0 23 12 0 0 0 % I
% Lys: 0 0 0 0 56 12 0 12 0 0 0 0 0 12 0 % K
% Leu: 0 78 12 0 0 78 12 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 12 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 67 0 12 0 % N
% Pro: 0 0 0 78 0 0 12 12 78 78 0 12 0 0 0 % P
% Gln: 0 0 0 0 12 12 0 0 0 12 0 0 0 0 0 % Q
% Arg: 0 0 12 0 12 0 0 0 0 12 0 0 12 45 23 % R
% Ser: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 12 0 23 12 0 67 56 0 0 0 0 56 0 0 % T
% Val: 0 0 56 0 12 0 0 0 0 0 78 0 12 0 45 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _