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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX38 All Species: 22.73
Human Site: S676 Identified Species: 38.46
UniProt: Q92620 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92620 NP_054722.2 1227 140503 S676 R E V V A R R S D L K L I V T
Chimpanzee Pan troglodytes Q7YR39 1044 119631 A556 L K V L V A S A T M D T A R F
Rhesus Macaque Macaca mulatta XP_001097681 1323 150587 S772 R E V V A R R S D L K L I V T
Dog Lupus familis XP_536800 1226 140550 S675 R E V V A R R S D L K L I V T
Cat Felis silvestris
Mouse Mus musculus A2A4P0 1244 142553 Q733 K K T V Q K R Q D M K L I V T
Rat Rattus norvegicus Q5XI69 779 88496 L291 E I E K S C E L L F Q M A E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025753 1230 141019 S679 R E V V A R R S D L K L V V T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957170 1258 143711 S707 R E V V S R R S D L K L I V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572947 1222 139562 H678 R E I V A R R H D L K L I V T
Honey Bee Apis mellifera XP_001122500 1093 125136 A605 M D S S K F S A F F G N A A T
Nematode Worm Caenorhab. elegans P34498 1131 129405 V621 I P G R T F P V E L F H A R T
Sea Urchin Strong. purpuratus XP_786478 1200 137247 T677 R E V V A R R T D M K L I V T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 L659 K K L M K R R L D L R L I V T
Baker's Yeast Sacchar. cerevisiae P15938 1071 121634 L583 I E T T F D T L Q E K F L Q V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37 92.2 97.7 N.A. 37.7 22.6 N.A. N.A. 89.8 N.A. 81.3 N.A. 62.3 58.1 55.5 68.4
Protein Similarity: 100 53.7 92.6 99.1 N.A. 55.7 37.3 N.A. N.A. 95.1 N.A. 89.9 N.A. 77.3 72.1 71.3 81
P-Site Identity: 100 6.6 100 100 N.A. 53.3 0 N.A. N.A. 93.3 N.A. 93.3 N.A. 86.6 6.6 13.3 86.6
P-Site Similarity: 100 33.3 100 100 N.A. 80 26.6 N.A. N.A. 100 N.A. 100 N.A. 93.3 20 20 100
Percent
Protein Identity: N.A. N.A. N.A. 36.1 36.8 N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 55 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 43 8 0 15 0 0 0 0 29 8 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 0 0 65 0 8 0 0 0 0 % D
% Glu: 8 58 8 0 0 0 8 0 8 8 0 0 0 8 0 % E
% Phe: 0 0 0 0 8 15 0 0 8 15 8 8 0 0 8 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % H
% Ile: 15 8 8 0 0 0 0 0 0 0 0 0 58 0 0 % I
% Lys: 15 22 0 8 15 8 0 0 0 0 65 0 0 0 0 % K
% Leu: 8 0 8 8 0 0 0 22 8 58 0 65 8 0 0 % L
% Met: 8 0 0 8 0 0 0 0 0 22 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 8 8 0 8 0 0 8 0 % Q
% Arg: 50 0 0 8 0 58 65 0 0 0 8 0 0 15 0 % R
% Ser: 0 0 8 8 15 0 15 36 0 0 0 0 0 0 8 % S
% Thr: 0 0 15 8 8 0 8 8 8 0 0 8 0 0 79 % T
% Val: 0 0 50 58 8 0 0 8 0 0 0 0 8 65 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _