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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0226
All Species:
16.36
Human Site:
S378
Identified Species:
36
UniProt:
Q92622
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92622
NP_001139114.1
972
108562
S378
D
Q
E
G
G
G
E
S
Q
L
S
S
V
L
R
Chimpanzee
Pan troglodytes
XP_516982
1143
125508
S534
D
Q
E
G
G
G
E
S
Q
L
S
S
V
L
R
Rhesus Macaque
Macaca mulatta
XP_001106158
1083
121122
S409
D
Q
E
G
G
E
E
S
Q
L
S
S
V
L
R
Dog
Lupus familis
XP_851560
1060
117667
S451
E
Q
E
G
D
G
Q
S
Q
L
S
S
I
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80U62
956
106841
S380
D
Q
E
E
G
R
Q
S
Q
A
G
S
V
L
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521256
412
44824
Chicken
Gallus gallus
XP_422730
944
105288
G373
D
R
G
A
N
G
C
G
S
R
G
L
G
L
L
Frog
Xenopus laevis
Q08AW4
748
85595
L229
A
E
I
S
Q
Y
E
L
H
I
Y
G
S
D
Y
Zebra Danio
Brachydanio rerio
XP_002666415
424
47031
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397109
841
96299
P322
E
I
E
I
S
Q
K
P
R
R
K
T
S
F
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796202
1067
119424
R484
R
Q
A
K
P
L
H
R
R
S
S
E
E
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
85.5
84.8
N.A.
85.3
N.A.
N.A.
25.5
70.7
21.9
22.9
N.A.
N.A.
33
N.A.
36.7
Protein Similarity:
100
84.2
86.6
87.3
N.A.
89.4
N.A.
N.A.
32.2
79.4
38.2
30.3
N.A.
N.A.
50
N.A.
52.2
P-Site Identity:
100
100
93.3
73.3
N.A.
66.6
N.A.
N.A.
0
20
6.6
0
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
93.3
93.3
N.A.
73.3
N.A.
N.A.
0
26.6
20
0
N.A.
N.A.
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
46
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% D
% Glu:
19
10
55
10
0
10
37
0
0
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
37
37
37
0
10
0
0
19
10
10
0
0
% G
% His:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% H
% Ile:
0
10
10
10
0
0
0
0
0
10
0
0
10
0
0
% I
% Lys:
0
0
0
10
0
0
10
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
10
0
37
0
10
0
64
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
55
0
0
10
10
19
0
46
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
10
0
10
19
19
0
0
0
0
46
% R
% Ser:
0
0
0
10
10
0
0
46
10
10
46
46
19
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
37
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _