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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0226 All Species: 17.88
Human Site: S410 Identified Species: 39.33
UniProt: Q92622 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92622 NP_001139114.1 972 108562 S410 K S H I R S H S D T S I A S R
Chimpanzee Pan troglodytes XP_516982 1143 125508 S566 K S H I R S H S D T S I A S R
Rhesus Macaque Macaca mulatta XP_001106158 1083 121122 S441 K S H I R S H S D T S I A S R
Dog Lupus familis XP_851560 1060 117667 S483 K S H T R S H S D T N I A S R
Cat Felis silvestris
Mouse Mus musculus Q80U62 956 106841 S412 K S H I R S H S D T N I A S R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521256 412 44824
Chicken Gallus gallus XP_422730 944 105288 H405 K K S H V R S H S D T N V A S
Frog Xenopus laevis Q08AW4 748 85595 E261 I T I T G S H E T K L V N V I
Zebra Danio Brachydanio rerio XP_002666415 424 47031
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397109 841 96299 K354 Q K D I R T P K K T F M E D G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796202 1067 119424 I516 A R S M S D Q I T N V R G G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.9 85.5 84.8 N.A. 85.3 N.A. N.A. 25.5 70.7 21.9 22.9 N.A. N.A. 33 N.A. 36.7
Protein Similarity: 100 84.2 86.6 87.3 N.A. 89.4 N.A. N.A. 32.2 79.4 38.2 30.3 N.A. N.A. 50 N.A. 52.2
P-Site Identity: 100 100 100 86.6 N.A. 93.3 N.A. N.A. 0 6.6 13.3 0 N.A. N.A. 20 N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 100 N.A. N.A. 0 20 26.6 0 N.A. N.A. 40 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 0 0 46 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 10 0 0 46 10 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 0 0 0 0 10 10 19 % G
% His: 0 0 46 10 0 0 55 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 10 46 0 0 0 10 0 0 0 46 0 0 10 % I
% Lys: 55 19 0 0 0 0 0 10 10 10 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 19 10 10 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 55 10 0 0 0 0 0 10 0 0 46 % R
% Ser: 0 46 19 0 10 55 10 46 10 0 28 0 0 46 10 % S
% Thr: 0 10 0 19 0 10 0 0 19 55 10 0 0 0 0 % T
% Val: 0 0 0 0 10 0 0 0 0 0 10 10 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _