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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0226 All Species: 9.39
Human Site: S469 Identified Species: 20.67
UniProt: Q92622 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92622 NP_001139114.1 972 108562 S469 E G M F R R P S E G Q S L I S
Chimpanzee Pan troglodytes XP_516982 1143 125508 G625 S L Y M E Y E G G R Y L C S G
Rhesus Macaque Macaca mulatta XP_001106158 1083 121122 S500 E G M F R R P S E G Q S L I S
Dog Lupus familis XP_851560 1060 117667 G542 S L Y M E Y E G G Q Y L C S G
Cat Felis silvestris
Mouse Mus musculus Q80U62 956 106841 C471 S E Q D F G S C A D L E K E N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521256 412 44824
Chicken Gallus gallus XP_422730 944 105288 S464 L S E Q D F G S C A D L E K E
Frog Xenopus laevis Q08AW4 748 85595 S320 L K K Q N N F S D G I R G C M
Zebra Danio Brachydanio rerio XP_002666415 424 47031
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397109 841 96299 A413 S I S E A M I A A I E Q V K C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796202 1067 119424 S575 D G Y F P Q P S Q G E S L F T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.9 85.5 84.8 N.A. 85.3 N.A. N.A. 25.5 70.7 21.9 22.9 N.A. N.A. 33 N.A. 36.7
Protein Similarity: 100 84.2 86.6 87.3 N.A. 89.4 N.A. N.A. 32.2 79.4 38.2 30.3 N.A. N.A. 50 N.A. 52.2
P-Site Identity: 100 0 100 0 N.A. 0 N.A. N.A. 0 6.6 13.3 0 N.A. N.A. 0 N.A. 46.6
P-Site Similarity: 100 0 100 0 N.A. 6.6 N.A. N.A. 0 6.6 20 0 N.A. N.A. 20 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 10 19 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 10 0 0 0 19 10 10 % C
% Asp: 10 0 0 10 10 0 0 0 10 10 10 0 0 0 0 % D
% Glu: 19 10 10 10 19 0 19 0 19 0 19 10 10 10 10 % E
% Phe: 0 0 0 28 10 10 10 0 0 0 0 0 0 10 0 % F
% Gly: 0 28 0 0 0 10 10 19 19 37 0 0 10 0 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 10 0 0 10 10 0 0 19 0 % I
% Lys: 0 10 10 0 0 0 0 0 0 0 0 0 10 19 0 % K
% Leu: 19 19 0 0 0 0 0 0 0 0 10 28 28 0 0 % L
% Met: 0 0 19 19 0 10 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 10 0 28 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 19 0 10 0 0 10 10 19 10 0 0 0 % Q
% Arg: 0 0 0 0 19 19 0 0 0 10 0 10 0 0 0 % R
% Ser: 37 10 10 0 0 0 10 46 0 0 0 28 0 19 19 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 28 0 0 19 0 0 0 0 19 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _