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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0226
All Species:
6.36
Human Site:
S497
Identified Species:
14
UniProt:
Q92622
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92622
NP_001139114.1
972
108562
S497
E
K
E
N
A
H
F
S
I
S
E
S
L
I
A
Chimpanzee
Pan troglodytes
XP_516982
1143
125508
D653
I
S
Y
L
S
E
Q
D
F
G
S
C
A
D
L
Rhesus Macaque
Macaca mulatta
XP_001106158
1083
121122
S528
E
K
E
N
A
H
F
S
I
S
E
S
L
I
A
Dog
Lupus familis
XP_851560
1060
117667
D570
I
S
Y
L
S
E
Q
D
F
G
S
C
A
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80U62
956
106841
M499
E
L
M
K
C
N
M
M
S
Q
C
L
E
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521256
412
44824
R12
P
G
S
V
R
I
K
R
R
S
R
S
K
T
I
Chicken
Gallus gallus
XP_422730
944
105288
M492
I
E
L
M
K
C
N
M
M
S
R
Q
L
E
E
Frog
Xenopus laevis
Q08AW4
748
85595
N348
I
S
N
G
N
Q
K
N
I
I
K
T
G
T
L
Zebra Danio
Brachydanio rerio
XP_002666415
424
47031
T24
K
L
L
Y
N
L
K
T
T
V
E
G
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397109
841
96299
L441
S
D
E
E
I
N
S
L
K
Q
R
I
R
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796202
1067
119424
C603
D
K
E
N
A
H
F
C
I
S
E
A
I
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
85.5
84.8
N.A.
85.3
N.A.
N.A.
25.5
70.7
21.9
22.9
N.A.
N.A.
33
N.A.
36.7
Protein Similarity:
100
84.2
86.6
87.3
N.A.
89.4
N.A.
N.A.
32.2
79.4
38.2
30.3
N.A.
N.A.
50
N.A.
52.2
P-Site Identity:
100
0
100
0
N.A.
6.6
N.A.
N.A.
13.3
13.3
6.6
13.3
N.A.
N.A.
6.6
N.A.
73.3
P-Site Similarity:
100
6.6
100
6.6
N.A.
13.3
N.A.
N.A.
13.3
26.6
26.6
40
N.A.
N.A.
20
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
28
0
0
0
0
0
0
10
19
0
28
% A
% Cys:
0
0
0
0
10
10
0
10
0
0
10
19
0
0
0
% C
% Asp:
10
10
0
0
0
0
0
19
0
0
0
0
0
19
0
% D
% Glu:
28
10
37
10
0
19
0
0
0
0
37
0
10
19
19
% E
% Phe:
0
0
0
0
0
0
28
0
19
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
0
0
0
0
19
0
10
10
0
0
% G
% His:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% H
% Ile:
37
0
0
0
10
10
0
0
37
10
0
10
10
28
10
% I
% Lys:
10
28
0
10
10
0
28
0
10
0
10
0
10
0
0
% K
% Leu:
0
19
19
19
0
10
0
10
0
0
0
10
37
19
28
% L
% Met:
0
0
10
10
0
0
10
19
10
0
0
0
0
0
0
% M
% Asn:
0
0
10
28
19
19
10
10
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
19
0
0
19
0
10
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
10
10
0
28
0
10
0
10
% R
% Ser:
10
28
10
0
19
0
10
19
10
46
19
28
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
10
10
0
0
10
0
19
0
% T
% Val:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
19
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _