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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0226 All Species: 25.76
Human Site: S851 Identified Species: 56.67
UniProt: Q92622 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92622 NP_001139114.1 972 108562 S851 T E D L H L Y S L N D L T A T
Chimpanzee Pan troglodytes XP_516982 1143 125508 S1022 T E D L H L Y S L N D L T A T
Rhesus Macaque Macaca mulatta XP_001106158 1083 121122 S927 T E D L H L Y S L N D L T A T
Dog Lupus familis XP_851560 1060 117667 S939 T E D L H L Y S L N D L T A T
Cat Felis silvestris
Mouse Mus musculus Q80U62 956 106841 S835 T E D L H L Y S L S D L T A T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521256 412 44824 R318 A I G N L G C R G R A A S C Q
Chicken Gallus gallus XP_422730 944 105288 S827 T E D L H L Y S L S D L S A T
Frog Xenopus laevis Q08AW4 748 85595 A654 L L K I I K F A T S H V Y S C
Zebra Danio Brachydanio rerio XP_002666415 424 47031 A330 S F S E A Q K A T G R S S R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397109 841 96299 T747 F F K D F L F T Y L M H V K Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796202 1067 119424 S959 M G Q P D L Y S L S D L L N V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.9 85.5 84.8 N.A. 85.3 N.A. N.A. 25.5 70.7 21.9 22.9 N.A. N.A. 33 N.A. 36.7
Protein Similarity: 100 84.2 86.6 87.3 N.A. 89.4 N.A. N.A. 32.2 79.4 38.2 30.3 N.A. N.A. 50 N.A. 52.2
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. 0 86.6 0 0 N.A. N.A. 6.6 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 6.6 100 40 20 N.A. N.A. 20 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 0 0 19 0 0 10 10 0 55 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 10 % C
% Asp: 0 0 55 10 10 0 0 0 0 0 64 0 0 0 0 % D
% Glu: 0 55 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 19 0 0 10 0 19 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 0 0 10 0 0 10 10 0 0 0 0 10 % G
% His: 0 0 0 0 55 0 0 0 0 0 10 10 0 0 0 % H
% Ile: 0 10 0 10 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 19 0 0 10 10 0 0 0 0 0 0 10 0 % K
% Leu: 10 10 0 55 10 73 0 0 64 10 0 64 10 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 37 0 0 0 10 0 % N
% Pro: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 10 0 10 10 0 0 10 0 % R
% Ser: 10 0 10 0 0 0 0 64 0 37 0 10 28 10 0 % S
% Thr: 55 0 0 0 0 0 0 10 19 0 0 0 46 0 55 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 64 0 10 0 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _