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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXDN All Species: 22.12
Human Site: S483 Identified Species: 40.56
UniProt: Q92626 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92626 NP_036425.1 1479 165275 S483 D R R H L V L S S G T L R I S
Chimpanzee Pan troglodytes XP_001169397 866 97623
Rhesus Macaque Macaca mulatta XP_001108296 1316 146985 N387 S S G L Y L Q N I T Q R D H G
Dog Lupus familis XP_544073 1296 144318 P366 S C H A E G E P Q P I I T W N
Cat Felis silvestris
Mouse Mus musculus Q3UQ28 1475 165115 S480 D R R H L V L S S G T L R I S
Rat Rattus norvegicus XP_002726775 1475 165020 S480 D R R H L V L S S G T L R I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514779 1469 164647 S470 E G Q H T I L S S G T L R L A
Chicken Gallus gallus XP_419931 1456 163977 S459 D R R H L V L S S G T L R I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665312 1530 170912 S466 D R R H V V L S T G S L R I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ4 1527 170496 V516 N E N T E L V V G A A R Q E H
Honey Bee Apis mellifera XP_396476 1293 147180 W364 R P T P N I Q W W R N G Q L L
Nematode Worm Caenorhab. elegans Q1ENI8 1285 146318 I356 Y H N G K R F I S S R K R Q L
Sea Urchin Strong. purpuratus XP_797821 1402 156847 A464 D R K F L I L A S G T L R I I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.4 56 55.8 N.A. 91 89.7 N.A. 65.4 83.4 N.A. 67.8 N.A. 41.5 40.7 36.1 46.5
Protein Similarity: 100 58.4 68.4 66.8 N.A. 94.6 93.2 N.A. 78.5 89.7 N.A. 80.3 N.A. 57.8 56.7 51 60.6
P-Site Identity: 100 0 0 0 N.A. 100 100 N.A. 53.3 100 N.A. 80 N.A. 0 0 13.3 66.6
P-Site Similarity: 100 0 13.3 13.3 N.A. 100 100 N.A. 86.6 100 N.A. 100 N.A. 26.6 20 13.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 8 0 8 8 0 0 0 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 47 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 8 8 0 0 16 0 8 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 8 0 8 0 0 8 54 0 8 0 0 8 % G
% His: 0 8 8 47 0 0 0 0 0 0 0 0 0 8 8 % H
% Ile: 0 0 0 0 0 24 0 8 8 0 8 8 0 47 8 % I
% Lys: 0 0 8 0 8 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 0 0 0 8 39 16 54 0 0 0 0 54 0 16 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 16 0 8 0 0 8 0 0 8 0 0 0 8 % N
% Pro: 0 8 0 8 0 0 0 8 0 8 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 16 0 8 0 8 0 16 8 0 % Q
% Arg: 8 47 39 0 0 8 0 0 0 8 8 16 62 0 0 % R
% Ser: 16 8 0 0 0 0 0 47 54 8 8 0 0 0 39 % S
% Thr: 0 0 8 8 8 0 0 0 8 8 47 0 8 0 0 % T
% Val: 0 0 0 0 8 39 8 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 8 0 0 0 0 8 0 % W
% Tyr: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _