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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXDN
All Species:
17.58
Human Site:
S490
Identified Species:
32.22
UniProt:
Q92626
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92626
NP_036425.1
1479
165275
S490
S
S
G
T
L
R
I
S
G
V
A
L
H
D
Q
Chimpanzee
Pan troglodytes
XP_001169397
866
97623
Rhesus Macaque
Macaca mulatta
XP_001108296
1316
146985
G394
N
I
T
Q
R
D
H
G
R
F
T
C
H
A
N
Dog
Lupus familis
XP_544073
1296
144318
N373
P
Q
P
I
I
T
W
N
K
A
G
V
Q
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3UQ28
1475
165115
S487
S
S
G
T
L
R
I
S
G
V
A
L
H
D
Q
Rat
Rattus norvegicus
XP_002726775
1475
165020
S487
S
S
G
T
L
R
I
S
G
V
A
L
H
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514779
1469
164647
A477
S
S
G
T
L
R
L
A
P
V
A
Q
H
D
Q
Chicken
Gallus gallus
XP_419931
1456
163977
S466
S
S
G
T
L
R
I
S
R
V
A
L
H
D
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665312
1530
170912
S473
S
T
G
S
L
R
I
S
R
V
A
L
H
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZZ4
1527
170496
H523
V
G
A
A
R
Q
E
H
A
G
V
Y
R
C
T
Honey Bee
Apis mellifera
XP_396476
1293
147180
L371
W
W
R
N
G
Q
L
L
N
V
G
G
R
V
A
Nematode Worm
Caenorhab. elegans
Q1ENI8
1285
146318
L363
I
S
S
R
K
R
Q
L
G
L
S
N
N
V
L
Sea Urchin
Strong. purpuratus
XP_797821
1402
156847
I471
A
S
G
T
L
R
I
I
R
V
S
Q
E
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.4
56
55.8
N.A.
91
89.7
N.A.
65.4
83.4
N.A.
67.8
N.A.
41.5
40.7
36.1
46.5
Protein Similarity:
100
58.4
68.4
66.8
N.A.
94.6
93.2
N.A.
78.5
89.7
N.A.
80.3
N.A.
57.8
56.7
51
60.6
P-Site Identity:
100
0
6.6
0
N.A.
100
100
N.A.
73.3
93.3
N.A.
80
N.A.
0
6.6
20
53.3
P-Site Similarity:
100
0
13.3
20
N.A.
100
100
N.A.
86.6
93.3
N.A.
93.3
N.A.
6.6
20
40
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
0
0
8
8
8
47
0
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
54
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
8
54
0
8
0
0
8
31
8
16
8
0
0
0
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
0
54
0
0
% H
% Ile:
8
8
0
8
8
0
47
8
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
54
0
16
16
0
8
0
39
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
8
8
0
0
8
8
0
8
% N
% Pro:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
16
8
0
0
0
0
16
8
0
47
% Q
% Arg:
0
0
8
8
16
62
0
0
31
0
0
0
16
0
0
% R
% Ser:
47
54
8
8
0
0
0
39
0
0
16
0
0
0
0
% S
% Thr:
0
8
8
47
0
8
0
0
0
0
8
0
0
0
16
% T
% Val:
8
0
0
0
0
0
0
0
0
62
8
8
0
16
0
% V
% Trp:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _