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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXDN All Species: 30
Human Site: T989 Identified Species: 55
UniProt: Q92626 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92626 NP_036425.1 1479 165275 T989 L G L T S M H T L W F R E H N
Chimpanzee Pan troglodytes XP_001169397 866 97623 L434 G E V G M R T L G E Y H G Y D
Rhesus Macaque Macaca mulatta XP_001108296 1316 146985 R884 K V G S V Y A R E Q I N Q Q T
Dog Lupus familis XP_544073 1296 144318 L863 G E P G M R M L R D Y Q G Y D
Cat Felis silvestris
Mouse Mus musculus Q3UQ28 1475 165115 T986 L G L T S M H T L W F R E H N
Rat Rattus norvegicus XP_002726775 1475 165020 T986 L G L T S M H T L W F R E H N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514779 1469 164647 T976 L A L T A M H T L W F R E H N
Chicken Gallus gallus XP_419931 1456 163977 T965 L G L T S I H T L W F R E H N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665312 1530 170912 T1046 L G L T A M H T V W L R E H N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ4 1527 170496 T1024 V G L L A M H T I W M R E H N
Honey Bee Apis mellifera XP_396476 1293 147180 I861 R N P I E S T I N C F V A G D
Nematode Worm Caenorhab. elegans Q1ENI8 1285 146318 M853 P F E K D S N M D C R R N F S
Sea Urchin Strong. purpuratus XP_797821 1402 156847 T970 L G L L S L H T V W M R E H N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.4 56 55.8 N.A. 91 89.7 N.A. 65.4 83.4 N.A. 67.8 N.A. 41.5 40.7 36.1 46.5
Protein Similarity: 100 58.4 68.4 66.8 N.A. 94.6 93.2 N.A. 78.5 89.7 N.A. 80.3 N.A. 57.8 56.7 51 60.6
P-Site Identity: 100 0 0 0 N.A. 100 100 N.A. 86.6 93.3 N.A. 80 N.A. 66.6 6.6 6.6 73.3
P-Site Similarity: 100 26.6 13.3 26.6 N.A. 100 100 N.A. 93.3 100 N.A. 93.3 N.A. 86.6 13.3 20 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 24 0 8 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 8 8 0 0 0 0 24 % D
% Glu: 0 16 8 0 8 0 0 0 8 8 0 0 62 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 47 0 0 8 0 % F
% Gly: 16 54 8 16 0 0 0 0 8 0 0 0 16 8 0 % G
% His: 0 0 0 0 0 0 62 0 0 0 0 8 0 62 0 % H
% Ile: 0 0 0 8 0 8 0 8 8 0 8 0 0 0 0 % I
% Lys: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 54 0 62 16 0 8 0 16 39 0 8 0 0 0 0 % L
% Met: 0 0 0 0 16 47 8 8 0 0 16 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 8 0 8 0 0 8 8 0 62 % N
% Pro: 8 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 8 8 8 0 % Q
% Arg: 8 0 0 0 0 16 0 8 8 0 8 70 0 0 0 % R
% Ser: 0 0 0 8 39 16 0 0 0 0 0 0 0 0 8 % S
% Thr: 0 0 0 47 0 0 16 62 0 0 0 0 0 0 8 % T
% Val: 8 8 8 0 8 0 0 0 16 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 62 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 16 0 0 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _