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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXDN All Species: 22.73
Human Site: Y1173 Identified Species: 41.67
UniProt: Q92626 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92626 NP_036425.1 1479 165275 Y1173 G I P P Y H D Y R V Y C N L S
Chimpanzee Pan troglodytes XP_001169397 866 97623 Y592 R E K L K R L Y G S T L N I D
Rhesus Macaque Macaca mulatta XP_001108296 1316 146985 A1042 G Y N P N V N A G I I N S F A
Dog Lupus familis XP_544073 1296 144318 Y1021 R R K L K K L Y G N P G N I D
Cat Felis silvestris
Mouse Mus musculus Q3UQ28 1475 165115 Y1170 G I P P Y H D Y R V Y C N L S
Rat Rattus norvegicus XP_002726775 1475 165020 Y1170 G I P P Y H D Y R V Y C N L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514779 1469 164647 Y1160 G I P P Y V D Y R V F C N L T
Chicken Gallus gallus XP_419931 1456 163977 F1149 G I P P Y H D F R V Y C N L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665312 1530 170912 Y1230 G I P S Y N D Y R V F C N L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ4 1527 170496 Y1208 G M P G Y N V Y R K L C N L T
Honey Bee Apis mellifera XP_396476 1293 147180 A1019 R G M F A T A A K L K L P E E
Nematode Worm Caenorhab. elegans Q1ENI8 1285 146318 G1011 P E L V L T Q G G V D P L L R
Sea Urchin Strong. purpuratus XP_797821 1402 156847 V1128 T E H L F E M V H E I A L D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.4 56 55.8 N.A. 91 89.7 N.A. 65.4 83.4 N.A. 67.8 N.A. 41.5 40.7 36.1 46.5
Protein Similarity: 100 58.4 68.4 66.8 N.A. 94.6 93.2 N.A. 78.5 89.7 N.A. 80.3 N.A. 57.8 56.7 51 60.6
P-Site Identity: 100 13.3 13.3 13.3 N.A. 100 100 N.A. 80 93.3 N.A. 73.3 N.A. 53.3 0 13.3 0
P-Site Similarity: 100 20 40 20 N.A. 100 100 N.A. 93.3 100 N.A. 93.3 N.A. 73.3 13.3 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 8 16 0 0 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 54 0 0 0 % C
% Asp: 0 0 0 0 0 0 47 0 0 0 8 0 0 8 16 % D
% Glu: 0 24 0 0 0 8 0 0 0 8 0 0 0 8 8 % E
% Phe: 0 0 0 8 8 0 0 8 0 0 16 0 0 8 0 % F
% Gly: 62 8 0 8 0 0 0 8 31 0 0 8 0 0 0 % G
% His: 0 0 8 0 0 31 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 47 0 0 0 0 0 0 0 8 16 0 0 16 0 % I
% Lys: 0 0 16 0 16 8 0 0 8 8 8 0 0 0 0 % K
% Leu: 0 0 8 24 8 0 16 0 0 8 8 16 16 62 8 % L
% Met: 0 8 8 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 8 16 8 0 0 8 0 8 70 0 0 % N
% Pro: 8 0 54 47 0 0 0 0 0 0 8 8 8 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 24 8 0 0 0 8 0 0 54 0 0 0 0 0 8 % R
% Ser: 0 0 0 8 0 0 0 0 0 8 0 0 8 0 31 % S
% Thr: 8 0 0 0 0 16 0 0 0 0 8 0 0 0 24 % T
% Val: 0 0 0 8 0 16 8 8 0 54 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 54 0 0 62 0 0 31 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _