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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF3A All Species: 25.45
Human Site: Y189 Identified Species: 62.22
UniProt: Q92664 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92664 NP_002088.2 365 41515 Y189 H A K A H E G Y V C Q K G C S
Chimpanzee Pan troglodytes A2T759 682 76399 Y349 I H S G E K P Y V C S E C G K
Rhesus Macaque Macaca mulatta XP_001095556 426 47471 Y250 H A K T H E G Y V C Q K G C S
Dog Lupus familis XP_534523 557 62808 Y382 H G K V H E G Y M C Q K D K C
Cat Felis silvestris
Mouse Mus musculus Q8VHT7 364 41552 Y187 H G K V H E G Y L C Q K G C S
Rat Rattus norvegicus Q8VHT8 363 41368 Y187 H G K V H E G Y L C Q K G C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519471 476 53197 Y298 H E K M H A G Y T C R K G C S
Chicken Gallus gallus NP_001107043 374 41261 Y200 H K K T H E G Y A C K K E N C
Frog Xenopus laevis P03001 366 41892 Y184 H E K V H A G Y P C K K D D S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781539 526 59107 P246 Q H Q V V H K P G Y Q K P P A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.6 82.6 55.1 N.A. 77.5 79.1 N.A. 51.6 63.3 54.9 N.A. N.A. N.A. N.A. N.A. 21.2
Protein Similarity: 100 31.8 84 59.6 N.A. 86.3 86.3 N.A. 58.8 75.4 67.4 N.A. N.A. N.A. N.A. N.A. 33
P-Site Identity: 100 20 93.3 60 N.A. 80 80 N.A. 66.6 53.3 53.3 N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 33.3 93.3 66.6 N.A. 86.6 86.6 N.A. 73.3 60 60 N.A. N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 10 0 20 0 0 10 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 90 0 0 10 50 20 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 20 10 0 % D
% Glu: 0 20 0 0 10 60 0 0 0 0 0 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 30 0 10 0 0 80 0 10 0 0 0 50 10 0 % G
% His: 80 20 0 0 80 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 80 0 0 10 10 0 0 0 20 90 0 10 10 % K
% Leu: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 10 10 10 0 0 0 10 10 0 % P
% Gln: 10 0 10 0 0 0 0 0 0 0 60 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 60 % S
% Thr: 0 0 0 20 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 50 10 0 0 0 30 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 90 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _