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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SORL1
All Species:
18.79
Human Site:
S2178
Identified Species:
51.67
UniProt:
Q92673
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92673
NP_003096.1
2214
248441
S2178
A
F
A
N
S
H
Y
S
S
R
L
G
S
A
I
Chimpanzee
Pan troglodytes
XP_001156482
4034
452735
S3910
P
M
Y
S
A
R
D
S
A
V
K
V
V
Q
P
Rhesus Macaque
Macaca mulatta
XP_001102178
2223
249098
S2168
A
F
A
N
S
H
Y
S
S
R
L
G
W
S
P
Dog
Lupus familis
XP_536545
2204
246660
S2168
A
F
A
N
S
H
Y
S
S
R
L
G
S
A
I
Cat
Felis silvestris
Mouse
Mus musculus
O88307
2215
247103
S2179
A
F
A
N
S
H
Y
S
S
R
L
G
S
A
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505297
2152
240021
S2116
A
F
A
N
S
H
Y
S
S
R
L
G
S
A
I
Chicken
Gallus gallus
Q98930
1592
178392
P1557
L
R
V
P
E
G
L
P
D
A
P
F
N
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392519
2132
240955
D2097
Q
F
A
N
S
H
Y
D
T
R
R
G
Q
A
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198637
1175
132480
L1140
G
G
S
Q
C
V
P
L
S
W
E
C
D
H
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.2
92.2
92.6
N.A.
93.2
N.A.
N.A.
78.8
58.3
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
25.5
Protein Similarity:
100
32.5
94.1
96
N.A.
96.3
N.A.
N.A.
87.3
64.8
N.A.
N.A.
N.A.
N.A.
49.9
N.A.
35.8
P-Site Identity:
100
6.6
80
100
N.A.
100
N.A.
N.A.
100
0
N.A.
N.A.
N.A.
N.A.
60
N.A.
6.6
P-Site Similarity:
100
26.6
86.6
100
N.A.
100
N.A.
N.A.
100
6.6
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
56
0
67
0
12
0
0
0
12
12
0
0
0
56
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
12
12
0
0
0
12
0
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
67
0
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
12
12
0
0
0
12
0
0
0
0
0
67
0
0
0
% G
% His:
0
0
0
0
0
67
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
12
0
0
0
0
0
12
12
0
0
56
0
0
12
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
67
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
12
0
0
12
0
0
12
12
0
0
12
0
0
0
23
% P
% Gln:
12
0
0
12
0
0
0
0
0
0
0
0
12
12
12
% Q
% Arg:
0
12
0
0
0
12
0
0
0
67
12
0
0
0
0
% R
% Ser:
0
0
12
12
67
0
0
67
67
0
0
0
45
12
0
% S
% Thr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% T
% Val:
0
0
12
0
0
12
0
0
0
12
0
12
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% W
% Tyr:
0
0
12
0
0
0
67
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _