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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SORL1
All Species:
8.79
Human Site:
S318
Identified Species:
24.17
UniProt:
Q92673
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92673
NP_003096.1
2214
248441
S318
K
V
V
H
L
L
G
S
E
Q
Q
S
S
V
Q
Chimpanzee
Pan troglodytes
XP_001156482
4034
452735
W904
W
V
G
R
N
L
Y
W
T
D
Y
A
L
E
T
Rhesus Macaque
Macaca mulatta
XP_001102178
2223
249098
S308
K
V
V
H
L
L
G
S
Q
Q
Q
S
S
V
Q
Dog
Lupus familis
XP_536545
2204
246660
G308
K
A
V
H
L
L
G
G
L
Q
P
A
S
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
O88307
2215
247103
S318
K
V
V
H
L
P
G
S
Q
Q
Q
S
S
V
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505297
2152
240021
G264
V
Q
L
W
V
S
S
G
R
K
P
M
R
A
A
Chicken
Gallus gallus
Q98930
1592
178392
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392519
2132
240955
K293
R
F
A
T
S
K
K
K
N
E
T
E
H
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198637
1175
132480
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.2
92.2
92.6
N.A.
93.2
N.A.
N.A.
78.8
58.3
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
25.5
Protein Similarity:
100
32.5
94.1
96
N.A.
96.3
N.A.
N.A.
87.3
64.8
N.A.
N.A.
N.A.
N.A.
49.9
N.A.
35.8
P-Site Identity:
100
13.3
93.3
66.6
N.A.
86.6
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
20
100
73.3
N.A.
93.3
N.A.
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
20
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
0
0
0
0
0
0
0
23
0
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% D
% Glu:
0
0
0
0
0
0
0
0
12
12
0
12
0
12
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
45
23
0
0
0
0
0
0
0
% G
% His:
0
0
0
45
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
45
0
0
0
0
12
12
12
0
12
0
0
0
0
0
% K
% Leu:
0
0
12
0
45
45
0
0
12
0
0
0
12
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
12
0
0
0
0
23
0
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
23
45
34
0
0
0
45
% Q
% Arg:
12
0
0
12
0
0
0
0
12
0
0
0
12
0
0
% R
% Ser:
0
0
0
0
12
12
12
34
0
0
0
34
45
0
0
% S
% Thr:
0
0
0
12
0
0
0
0
12
0
12
0
0
0
12
% T
% Val:
12
45
45
0
12
0
0
0
0
0
0
0
0
45
0
% V
% Trp:
12
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _