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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SORL1
All Species:
13.64
Human Site:
S385
Identified Species:
37.5
UniProt:
Q92673
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92673
NP_003096.1
2214
248441
S385
E
G
L
K
F
S
L
S
L
E
N
V
L
Y
Y
Chimpanzee
Pan troglodytes
XP_001156482
4034
452735
I971
D
G
S
M
R
T
V
I
V
Q
D
K
I
F
W
Rhesus Macaque
Macaca mulatta
XP_001102178
2223
249098
S375
E
G
L
K
F
S
L
S
L
E
N
V
L
Y
Y
Dog
Lupus familis
XP_536545
2204
246660
S375
E
G
L
K
F
S
L
S
L
E
N
V
L
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
O88307
2215
247103
S385
E
G
L
K
F
S
L
S
L
E
N
V
L
Y
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505297
2152
240021
G331
Y
F
S
P
G
G
A
G
S
D
T
L
V
R
Y
Chicken
Gallus gallus
Q98930
1592
178392
F59
F
K
K
I
S
E
R
F
S
F
G
D
G
N
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392519
2132
240955
F360
I
D
Q
K
T
A
T
F
T
L
S
L
E
G
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198637
1175
132480
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.2
92.2
92.6
N.A.
93.2
N.A.
N.A.
78.8
58.3
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
25.5
Protein Similarity:
100
32.5
94.1
96
N.A.
96.3
N.A.
N.A.
87.3
64.8
N.A.
N.A.
N.A.
N.A.
49.9
N.A.
35.8
P-Site Identity:
100
6.6
100
100
N.A.
100
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
66.6
100
100
N.A.
100
N.A.
N.A.
26.6
0
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
0
0
0
0
0
0
12
12
12
0
0
0
% D
% Glu:
45
0
0
0
0
12
0
0
0
45
0
0
12
0
0
% E
% Phe:
12
12
0
0
45
0
0
23
0
12
0
0
0
12
0
% F
% Gly:
0
56
0
0
12
12
0
12
0
0
12
0
12
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
12
0
0
0
12
0
0
0
0
12
0
12
% I
% Lys:
0
12
12
56
0
0
0
0
0
0
0
12
0
0
0
% K
% Leu:
0
0
45
0
0
0
45
0
45
12
0
23
45
0
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
45
0
0
12
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
12
0
0
0
0
0
0
12
0
% R
% Ser:
0
0
23
0
12
45
0
45
23
0
12
0
0
0
12
% S
% Thr:
0
0
0
0
12
12
12
0
12
0
12
0
0
0
0
% T
% Val:
0
0
0
0
0
0
12
0
12
0
0
45
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
45
56
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _