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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SORL1
All Species:
18.79
Human Site:
Y1719
Identified Species:
51.67
UniProt:
Q92673
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92673
NP_003096.1
2214
248441
Y1719
N
L
L
V
N
T
L
Y
T
V
R
V
A
A
V
Chimpanzee
Pan troglodytes
XP_001156482
4034
452735
W2804
D
T
I
Y
W
T
D
W
N
T
R
T
V
E
K
Rhesus Macaque
Macaca mulatta
XP_001102178
2223
249098
Y1709
N
L
L
V
N
T
L
Y
T
V
R
V
A
A
V
Dog
Lupus familis
XP_536545
2204
246660
Y1709
N
L
L
V
N
A
P
Y
T
V
R
V
A
A
V
Cat
Felis silvestris
Mouse
Mus musculus
O88307
2215
247103
Y1719
N
L
L
L
N
A
L
Y
T
V
R
V
A
A
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505297
2152
240021
Y1657
N
L
M
V
D
T
L
Y
T
V
R
V
A
A
V
Chicken
Gallus gallus
Q98930
1592
178392
E1106
C
T
M
F
R
T
C
E
A
S
S
F
Q
C
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392519
2132
240955
S1633
F
E
A
G
K
N
Y
S
F
W
I
I
A
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198637
1175
132480
S689
G
F
M
E
R
E
G
S
Y
I
C
M
K
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.2
92.2
92.6
N.A.
93.2
N.A.
N.A.
78.8
58.3
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
25.5
Protein Similarity:
100
32.5
94.1
96
N.A.
96.3
N.A.
N.A.
87.3
64.8
N.A.
N.A.
N.A.
N.A.
49.9
N.A.
35.8
P-Site Identity:
100
13.3
100
86.6
N.A.
86.6
N.A.
N.A.
86.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
33.3
100
86.6
N.A.
93.3
N.A.
N.A.
100
20
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
23
0
0
12
0
0
0
67
56
0
% A
% Cys:
12
0
0
0
0
0
12
0
0
0
12
0
0
12
0
% C
% Asp:
12
0
0
0
12
0
12
0
0
0
0
0
0
12
0
% D
% Glu:
0
12
0
12
0
12
0
12
0
0
0
0
0
12
0
% E
% Phe:
12
12
0
12
0
0
0
0
12
0
0
12
0
0
0
% F
% Gly:
12
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
0
12
12
12
0
0
0
% I
% Lys:
0
0
0
0
12
0
0
0
0
0
0
0
12
12
12
% K
% Leu:
0
56
45
12
0
0
45
0
0
0
0
0
0
0
12
% L
% Met:
0
0
34
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
56
0
0
0
45
12
0
0
12
0
0
0
0
0
12
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
23
0
0
0
0
0
67
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
23
0
12
12
0
0
0
0
% S
% Thr:
0
23
0
0
0
56
0
0
56
12
0
12
0
0
0
% T
% Val:
0
0
0
45
0
0
0
0
0
56
0
56
12
0
56
% V
% Trp:
0
0
0
0
12
0
0
12
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
12
56
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _