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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG3 All Species: 12.12
Human Site: S255 Identified Species: 17.78
UniProt: Q92685 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92685 NP_005778.1 438 50126 S255 P F L L E N P S G Y L S R S F
Chimpanzee Pan troglodytes XP_516912 438 50083 S255 P F L L E N P S G Y L S R S F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535823 438 50017 I255 P F L L E N P I G Y L S R S F
Cat Felis silvestris
Mouse Mus musculus Q8K2A8 438 50148 I255 P F L L E N P I G Y L S R S F
Rat Rattus norvegicus NP_001135835 438 50162 V255 P F L L E N P V G Y L S R S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422759 385 44119 W214 Q F K W T V N W R F L P E E V
Frog Xenopus laevis NP_001106296 447 51149 T257 P F L L E N P T G Y L I R S F
Zebra Danio Brachydanio rerio NP_001018532 434 50115 V249 P F L L V N P V G Y V S R A F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27333 510 58442 V258 P F L L T H P V E Y L R G S F
Honey Bee Apis mellifera XP_001120233 436 51804 F257 P F L F H N P F A Y I K G A F
Nematode Worm Caenorhab. elegans NP_496950 640 74197 K234 P F L L Y D W K S Y L Q Q S F
Sea Urchin Strong. purpuratus XP_782048 425 50163 E242 P F L V A N P E A Y I L R S F
Poplar Tree Populus trichocarpa XP_002320351 423 48154 I234 P F L V S H P I A Y I S R A F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_182297 438 49224 V242 P F L I T Y P V S Y I A N A F
Baker's Yeast Sacchar. cerevisiae P38179 458 52842 Q269 P F L R S F P Q Q Y L H C A F
Red Bread Mold Neurospora crassa Q9C1K8 442 49462 T245 P F L A H Y P T E Y L S R A F
Conservation
Percent
Protein Identity: 100 98.8 N.A. 93.8 N.A. 88.5 87.6 N.A. N.A. 63.2 64.8 65.5 N.A. 44.1 47.9 30.3 55.2
Protein Similarity: 100 99.3 N.A. 96.3 N.A. 92.2 91.5 N.A. N.A. 71.6 76.7 78.3 N.A. 55.4 65 41.7 70
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. 13.3 86.6 73.3 N.A. 60 46.6 53.3 60
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. 20 93.3 86.6 N.A. 66.6 60 66.6 73.3
Percent
Protein Identity: 42.4 N.A. N.A. 44 35.5 40.2
Protein Similarity: 59.1 N.A. N.A. 60.5 50.4 57.9
P-Site Identity: 53.3 N.A. N.A. 40 46.6 60
P-Site Similarity: 80 N.A. N.A. 66.6 53.3 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 0 0 0 19 0 0 7 0 38 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 38 0 0 7 13 0 0 0 7 7 0 % E
% Phe: 0 100 0 7 0 7 0 7 0 7 0 0 0 0 94 % F
% Gly: 0 0 0 0 0 0 0 0 44 0 0 0 13 0 0 % G
% His: 0 0 0 0 13 13 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 19 0 0 25 7 0 0 0 % I
% Lys: 0 0 7 0 0 0 0 7 0 0 0 7 0 0 0 % K
% Leu: 0 0 94 57 0 0 0 0 0 0 69 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 57 7 0 0 0 0 0 7 0 0 % N
% Pro: 94 0 0 0 0 0 88 0 0 0 0 7 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 7 7 0 0 7 7 0 0 % Q
% Arg: 0 0 0 7 0 0 0 0 7 0 0 7 63 0 0 % R
% Ser: 0 0 0 0 13 0 0 13 13 0 0 50 0 57 0 % S
% Thr: 0 0 0 0 19 0 0 13 0 0 0 0 0 0 0 % T
% Val: 0 0 0 13 7 7 0 25 0 0 7 0 0 0 7 % V
% Trp: 0 0 0 7 0 0 7 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 13 0 0 0 94 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _