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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALG3
All Species:
28.18
Human Site:
S259
Identified Species:
41.33
UniProt:
Q92685
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92685
NP_005778.1
438
50126
S259
E
N
P
S
G
Y
L
S
R
S
F
D
L
G
R
Chimpanzee
Pan troglodytes
XP_516912
438
50083
S259
E
N
P
S
G
Y
L
S
R
S
F
D
L
G
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535823
438
50017
S259
E
N
P
I
G
Y
L
S
R
S
F
D
L
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2A8
438
50148
S259
E
N
P
I
G
Y
L
S
R
S
F
D
L
G
R
Rat
Rattus norvegicus
NP_001135835
438
50162
S259
E
N
P
V
G
Y
L
S
R
S
F
D
L
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422759
385
44119
P218
T
V
N
W
R
F
L
P
E
E
V
F
Q
H
R
Frog
Xenopus laevis
NP_001106296
447
51149
I261
E
N
P
T
G
Y
L
I
R
S
F
D
F
G
R
Zebra Danio
Brachydanio rerio
NP_001018532
434
50115
S253
V
N
P
V
G
Y
V
S
R
A
F
D
L
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27333
510
58442
R262
T
H
P
V
E
Y
L
R
G
S
F
D
L
G
R
Honey Bee
Apis mellifera
XP_001120233
436
51804
K261
H
N
P
F
A
Y
I
K
G
A
F
N
F
G
R
Nematode Worm
Caenorhab. elegans
NP_496950
640
74197
Q238
Y
D
W
K
S
Y
L
Q
Q
S
F
D
L
G
R
Sea Urchin
Strong. purpuratus
XP_782048
425
50163
L246
A
N
P
E
A
Y
I
L
R
S
F
E
L
S
R
Poplar Tree
Populus trichocarpa
XP_002320351
423
48154
S238
S
H
P
I
A
Y
I
S
R
A
F
N
L
G
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_182297
438
49224
A246
T
Y
P
V
S
Y
I
A
N
A
F
D
L
G
R
Baker's Yeast
Sacchar. cerevisiae
P38179
458
52842
H273
S
F
P
Q
Q
Y
L
H
C
A
F
N
F
G
R
Red Bread Mold
Neurospora crassa
Q9C1K8
442
49462
S249
H
Y
P
T
E
Y
L
S
R
A
F
E
L
S
R
Conservation
Percent
Protein Identity:
100
98.8
N.A.
93.8
N.A.
88.5
87.6
N.A.
N.A.
63.2
64.8
65.5
N.A.
44.1
47.9
30.3
55.2
Protein Similarity:
100
99.3
N.A.
96.3
N.A.
92.2
91.5
N.A.
N.A.
71.6
76.7
78.3
N.A.
55.4
65
41.7
70
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
80
73.3
N.A.
60
40
53.3
53.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
20
86.6
86.6
N.A.
66.6
60
66.6
66.6
Percent
Protein Identity:
42.4
N.A.
N.A.
44
35.5
40.2
Protein Similarity:
59.1
N.A.
N.A.
60.5
50.4
57.9
P-Site Identity:
53.3
N.A.
N.A.
46.6
40
53.3
P-Site Similarity:
80
N.A.
N.A.
66.6
53.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
19
0
0
7
0
38
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
0
0
63
0
0
0
% D
% Glu:
38
0
0
7
13
0
0
0
7
7
0
13
0
0
0
% E
% Phe:
0
7
0
7
0
7
0
0
0
0
94
7
19
0
0
% F
% Gly:
0
0
0
0
44
0
0
0
13
0
0
0
0
82
0
% G
% His:
13
13
0
0
0
0
0
7
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
19
0
0
25
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
69
7
0
0
0
0
75
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
57
7
0
0
0
0
0
7
0
0
19
0
0
0
% N
% Pro:
0
0
88
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
7
0
0
7
7
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
7
0
0
7
63
0
0
0
0
0
100
% R
% Ser:
13
0
0
13
13
0
0
50
0
57
0
0
0
13
0
% S
% Thr:
19
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
7
0
25
0
0
7
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
13
0
0
0
94
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _