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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG3 All Species: 25.15
Human Site: S430 Identified Species: 36.89
UniProt: Q92685 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92685 NP_005778.1 438 50126 S430 G P Q P F P K S T Q H S K K A
Chimpanzee Pan troglodytes XP_516912 438 50083 S430 G P Q P F P K S T Q H S K K A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535823 438 50017 S430 G P Q P F P K S V Q H S K K A
Cat Felis silvestris
Mouse Mus musculus Q8K2A8 438 50148 S430 S P E S F P K S I Q P S R K T
Rat Rattus norvegicus NP_001135835 438 50162 S430 S P Q F F P R S V Q P S R K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422759 385 44119 S377 P P Q P S K K S D P L S R K A
Frog Xenopus laevis NP_001106296 447 51149 T439 T W A S R P T T H T P T K R K
Zebra Danio Brachydanio rerio NP_001018532 434 50115 R426 N P A S P S H R S E N K A K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27333 510 58442 T491 V A K Q L I Q T M R I N N A A
Honey Bee Apis mellifera XP_001120233 436 51804 K429 L F G F M N K K C T N E K R K
Nematode Worm Caenorhab. elegans NP_496950 640 74197 N618 N T E K I E Q N S C K A E A S
Sea Urchin Strong. purpuratus XP_782048 425 50163 R409 L W R N K E E R R R A A A R S
Poplar Tree Populus trichocarpa XP_002320351 423 48154 E414 S E Y P Y V E E K L S T R K K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_182297 438 49224 K431 Y Q L K E H P K S Q I H K K A
Baker's Yeast Sacchar. cerevisiae P38179 458 52842 T449 L A K S H L R T T S S M E K K
Red Bread Mold Neurospora crassa Q9C1K8 442 49462 S432 E W E P G M K S S S K K E E A
Conservation
Percent
Protein Identity: 100 98.8 N.A. 93.8 N.A. 88.5 87.6 N.A. N.A. 63.2 64.8 65.5 N.A. 44.1 47.9 30.3 55.2
Protein Similarity: 100 99.3 N.A. 96.3 N.A. 92.2 91.5 N.A. N.A. 71.6 76.7 78.3 N.A. 55.4 65 41.7 70
P-Site Identity: 100 100 N.A. 93.3 N.A. 53.3 53.3 N.A. N.A. 53.3 13.3 13.3 N.A. 6.6 13.3 0 0
P-Site Similarity: 100 100 N.A. 93.3 N.A. 66.6 66.6 N.A. N.A. 60 33.3 40 N.A. 40 26.6 46.6 40
Percent
Protein Identity: 42.4 N.A. N.A. 44 35.5 40.2
Protein Similarity: 59.1 N.A. N.A. 60.5 50.4 57.9
P-Site Identity: 13.3 N.A. N.A. 26.6 13.3 26.6
P-Site Similarity: 40 N.A. N.A. 33.3 40 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 13 0 0 0 0 0 0 0 7 13 13 13 44 % A
% Cys: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % D
% Glu: 7 7 19 0 7 13 13 7 0 7 0 7 19 7 0 % E
% Phe: 0 7 0 13 32 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 19 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 7 7 7 0 7 0 19 7 0 0 0 % H
% Ile: 0 0 0 0 7 7 0 0 7 0 13 0 0 0 0 % I
% Lys: 0 0 13 13 7 7 44 13 7 0 13 13 38 63 25 % K
% Leu: 19 0 7 0 7 7 0 0 0 7 7 0 0 0 0 % L
% Met: 0 0 0 0 7 7 0 0 7 0 0 7 0 0 0 % M
% Asn: 13 0 0 7 0 7 0 7 0 0 13 7 7 0 0 % N
% Pro: 7 44 0 38 7 38 7 0 0 7 19 0 0 0 0 % P
% Gln: 0 7 32 7 0 0 13 0 0 38 0 0 0 0 0 % Q
% Arg: 0 0 7 0 7 0 13 13 7 13 0 0 25 19 0 % R
% Ser: 19 0 0 25 7 7 0 44 25 13 13 38 0 0 19 % S
% Thr: 7 7 0 0 0 0 7 19 19 13 0 13 0 0 13 % T
% Val: 7 0 0 0 0 7 0 0 13 0 0 0 0 0 0 % V
% Trp: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _