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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRCC
All Species:
30.3
Human Site:
S181
Identified Species:
60.61
UniProt:
Q92733
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92733
NP_005964.3
491
52418
S181
S
S
E
G
T
G
L
S
A
L
L
P
Q
P
K
Chimpanzee
Pan troglodytes
XP_001166951
465
48877
S181
S
S
E
G
T
G
L
S
A
L
L
P
Q
P
K
Rhesus Macaque
Macaca mulatta
XP_001116797
491
52356
S181
S
G
E
G
T
G
L
S
A
L
L
P
Q
P
K
Dog
Lupus familis
XP_851627
489
52096
S179
S
G
E
G
T
G
L
S
A
L
L
P
Q
P
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_291051
491
52283
S181
S
G
E
G
T
G
L
S
A
L
L
P
Q
P
K
Rat
Rattus norvegicus
NP_001101170
489
52102
S179
S
G
E
G
T
G
L
S
A
L
L
P
Q
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423657
512
54438
S196
R
G
E
G
S
G
L
S
A
L
L
P
Q
P
K
Frog
Xenopus laevis
NP_001084270
543
58416
S233
S
R
E
G
Y
G
L
S
A
L
L
P
Q
P
K
Zebra Danio
Brachydanio rerio
NP_001119912
392
43164
K112
S
S
L
L
P
Q
P
K
N
L
A
V
K
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647638
472
51508
S160
I
P
S
L
R
D
F
S
D
V
D
Q
E
K
A
Honey Bee
Apis mellifera
XP_001120938
399
45177
N119
K
E
N
E
L
K
C
N
K
L
K
P
S
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783288
538
58013
F172
S
T
K
G
V
G
L
F
A
M
L
P
K
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.4
99.3
95.3
N.A.
93.6
93
N.A.
N.A.
65
53.4
46
N.A.
23
24.4
N.A.
34.5
Protein Similarity:
100
92.6
99.5
97.1
N.A.
95.9
95.5
N.A.
N.A.
72.8
63.5
59.2
N.A.
34.6
40.9
N.A.
48.3
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
86.6
20
N.A.
6.6
20
N.A.
53.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
86.6
26.6
N.A.
20
26.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
75
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
9
0
9
0
0
0
0
% D
% Glu:
0
9
67
9
0
0
0
0
0
0
0
0
9
9
0
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% F
% Gly:
0
42
0
75
0
75
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
9
0
0
9
0
9
9
0
9
0
17
9
75
% K
% Leu:
0
0
9
17
9
0
75
0
0
84
75
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
9
9
0
0
0
0
9
0
% N
% Pro:
0
9
0
0
9
0
9
0
0
0
0
84
0
75
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
9
67
0
0
% Q
% Arg:
9
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
75
25
9
0
9
0
0
75
0
0
0
0
9
0
0
% S
% Thr:
0
9
0
0
50
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
9
0
0
0
0
9
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _