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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRCC
All Species:
24.55
Human Site:
S222
Identified Species:
49.09
UniProt:
Q92733
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92733
NP_005964.3
491
52418
S222
T
K
P
S
R
L
A
S
K
T
K
T
S
S
L
Chimpanzee
Pan troglodytes
XP_001166951
465
48877
S222
T
K
P
S
R
L
A
S
K
T
K
T
S
S
L
Rhesus Macaque
Macaca mulatta
XP_001116797
491
52356
S222
T
K
P
S
R
L
A
S
K
T
K
T
S
S
L
Dog
Lupus familis
XP_851627
489
52096
S220
T
K
P
S
R
Q
A
S
K
T
K
P
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_291051
491
52283
S222
A
K
P
S
R
L
A
S
K
T
K
P
A
S
L
Rat
Rattus norvegicus
NP_001101170
489
52102
S220
A
K
P
S
R
L
A
S
K
T
K
P
A
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423657
512
54438
T237
S
K
P
A
K
A
P
T
S
S
S
K
T
K
P
Frog
Xenopus laevis
NP_001084270
543
58416
K274
P
R
S
T
S
V
T
K
P
K
R
S
S
K
P
Zebra Danio
Brachydanio rerio
NP_001119912
392
43164
S153
S
L
S
G
S
S
P
S
P
S
A
I
K
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647638
472
51508
N201
S
E
R
N
F
S
K
N
S
S
S
A
V
A
Y
Honey Bee
Apis mellifera
XP_001120938
399
45177
N160
I
K
S
T
I
E
T
N
Q
T
K
V
S
F
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783288
538
58013
N213
P
P
G
K
P
P
G
N
P
L
A
P
V
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.4
99.3
95.3
N.A.
93.6
93
N.A.
N.A.
65
53.4
46
N.A.
23
24.4
N.A.
34.5
Protein Similarity:
100
92.6
99.5
97.1
N.A.
95.9
95.5
N.A.
N.A.
72.8
63.5
59.2
N.A.
34.6
40.9
N.A.
48.3
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
N.A.
13.3
6.6
6.6
N.A.
0
26.6
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
53.3
40
26.6
N.A.
40
53.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
0
9
50
0
0
0
17
9
17
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
9
9
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
0
0
0
0
0
9
0
0
9
% I
% Lys:
0
67
0
9
9
0
9
9
50
9
59
9
9
17
0
% K
% Leu:
0
9
0
0
0
42
0
0
0
9
0
0
0
0
59
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
25
0
0
0
0
0
0
0
% N
% Pro:
17
9
59
0
9
9
17
0
25
0
0
34
0
0
17
% P
% Gln:
0
0
0
0
0
9
0
0
9
0
0
0
0
9
0
% Q
% Arg:
0
9
9
0
50
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
25
0
25
50
17
17
0
59
17
25
17
9
50
50
0
% S
% Thr:
34
0
0
17
0
0
17
9
0
59
0
25
9
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
9
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _