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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRCC All Species: 30.3
Human Site: S476 Identified Species: 60.61
UniProt: Q92733 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92733 NP_005964.3 491 52418 S476 L E L K N T W S E N K L S R R
Chimpanzee Pan troglodytes XP_001166951 465 48877 L448 K V S G K R L L S G Q L G K L
Rhesus Macaque Macaca mulatta XP_001116797 491 52356 S476 L E L K N T W S E N K L S R R
Dog Lupus familis XP_851627 489 52096 S474 L E L K N T W S E N R L S R R
Cat Felis silvestris
Mouse Mus musculus NP_291051 491 52283 S476 L E L K N T W S E N K L S R R
Rat Rattus norvegicus NP_001101170 489 52102 S474 L E L K N T W S E N K L S R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423657 512 54438 S497 L E L K N T W S E N K L S R R
Frog Xenopus laevis NP_001084270 543 58416 S528 L E L K N S W S E N K M S R R
Zebra Danio Brachydanio rerio NP_001119912 392 43164 D378 E L K N N W A D N K L T R R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647638 472 51508 S457 A E L Q A M W S A N R Q T R R
Honey Bee Apis mellifera XP_001120938 399 45177 Q385 E L K N Q W A Q N R L T R K Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783288 538 58013 A522 L E L K N Q W A D N R A T R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.4 99.3 95.3 N.A. 93.6 93 N.A. N.A. 65 53.4 46 N.A. 23 24.4 N.A. 34.5
Protein Similarity: 100 92.6 99.5 97.1 N.A. 95.9 95.5 N.A. N.A. 72.8 63.5 59.2 N.A. 34.6 40.9 N.A. 48.3
P-Site Identity: 100 6.6 100 93.3 N.A. 100 100 N.A. N.A. 100 86.6 13.3 N.A. 46.6 0 N.A. 53.3
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. N.A. 100 100 20 N.A. 66.6 13.3 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 17 9 9 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % D
% Glu: 17 75 0 0 0 0 0 0 59 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 9 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 17 67 9 0 0 0 0 9 50 0 0 17 9 % K
% Leu: 67 17 75 0 0 0 9 9 0 0 17 59 0 0 9 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 17 75 0 0 0 17 75 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 9 9 9 0 9 0 0 9 9 0 0 17 % Q
% Arg: 0 0 0 0 0 9 0 0 0 9 25 0 17 84 67 % R
% Ser: 0 0 9 0 0 9 0 67 9 0 0 0 59 0 0 % S
% Thr: 0 0 0 0 0 50 0 0 0 0 0 17 17 0 0 % T
% Val: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 17 75 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _