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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TFG All Species: 8.48
Human Site: Y244 Identified Species: 26.67
UniProt: Q92734 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92734 NP_001007566.1 400 43448 Y244 G Q I E G Q M Y Q Q Y Q Q Q A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094395 400 43439 Y244 G Q I E G Q M Y Q Q Y Q Q Q A
Dog Lupus familis XP_545076 401 43287 Y245 G Q S E G Q M Y Q Q Y P Q Q A
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514541 396 42729 E240 Q A Q A G Q M E G Q M Y Q Q Y
Chicken Gallus gallus XP_416608 395 42569 Q239 G A Q P Q T G Q Q V E G Q M Y
Frog Xenopus laevis NP_001080421 409 44619 P253 Q Y P Q P Q Q P A G Y P A P Q
Zebra Danio Brachydanio rerio NP_956309 396 42179 D240 Q P P S T T M D G Q M Y Q Q Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799290 266 29554 L111 E S D Q L K N L R R E L Q S I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 95 N.A. N.A. N.A. N.A. 88.7 81.5 78.7 66.2 N.A. N.A. N.A. N.A. 39.7
Protein Similarity: 100 N.A. 99.7 96.5 N.A. N.A. N.A. N.A. 91.7 85.7 84.1 75.2 N.A. N.A. N.A. N.A. 49.7
P-Site Identity: 100 N.A. 100 86.6 N.A. N.A. N.A. N.A. 40 20 13.3 26.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 N.A. 100 86.6 N.A. N.A. N.A. N.A. 40 20 20 26.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 0 13 0 0 0 0 13 0 0 0 13 0 38 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 13 0 0 0 0 13 0 0 0 0 0 0 0 % D
% Glu: 13 0 0 38 0 0 0 13 0 0 25 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 50 0 0 0 50 0 13 0 25 13 0 13 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 13 % I
% Lys: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 13 0 0 13 0 0 0 13 0 0 0 % L
% Met: 0 0 0 0 0 0 63 0 0 0 25 0 0 13 0 % M
% Asn: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % N
% Pro: 0 13 25 13 13 0 0 13 0 0 0 25 0 13 0 % P
% Gln: 38 38 25 25 13 63 13 13 50 63 0 25 88 63 13 % Q
% Arg: 0 0 0 0 0 0 0 0 13 13 0 0 0 0 0 % R
% Ser: 0 13 13 13 0 0 0 0 0 0 0 0 0 13 0 % S
% Thr: 0 0 0 0 13 25 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 13 0 0 0 0 0 38 0 0 50 25 0 0 38 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _