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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RYR2
All Species:
9.39
Human Site:
T277
Identified Species:
41.33
UniProt:
Q92736
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92736
NP_001026
4965
564742
T277
R
S
L
W
R
L
E
T
L
R
V
A
W
S
G
Chimpanzee
Pan troglodytes
XP_514296
5018
570278
T325
R
S
L
W
R
L
E
T
L
R
V
A
W
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536330
4972
565017
T273
R
S
L
W
R
L
E
T
L
R
V
A
W
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_996757
4869
552752
R269
L
W
R
V
E
P
L
R
I
S
W
S
G
S
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24498
5127
580994
T269
E
L
A
R
T
K
W
T
G
G
F
I
N
W
Y
Honey Bee
Apis mellifera
XP_392217
5083
576621
L270
H
L
T
T
G
R
Y
L
G
V
K
E
N
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
N.A.
96.6
N.A.
N.A.
N.A.
N.A.
N.A.
67
N.A.
N.A.
N.A.
46.2
46.9
N.A.
N.A.
Protein Similarity:
100
97.9
N.A.
97.9
N.A.
N.A.
N.A.
N.A.
N.A.
80.6
N.A.
N.A.
N.A.
64.6
65.2
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
0
0
0
0
50
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
17
0
0
0
17
0
50
0
0
0
0
17
0
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% F
% Gly:
0
0
0
0
17
0
0
0
34
17
0
0
17
0
50
% G
% His:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
17
0
0
17
0
0
0
% I
% Lys:
0
0
0
0
0
17
0
0
0
0
17
0
0
0
0
% K
% Leu:
17
34
50
0
0
50
17
17
50
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
34
17
17
% N
% Pro:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
0
17
17
50
17
0
17
0
50
0
0
0
0
0
% R
% Ser:
0
50
0
0
0
0
0
0
0
17
0
17
0
67
0
% S
% Thr:
0
0
17
17
17
0
0
67
0
0
0
0
0
0
0
% T
% Val:
0
0
0
17
0
0
0
0
0
17
50
0
0
0
0
% V
% Trp:
0
17
0
50
0
0
17
0
0
0
17
0
50
17
0
% W
% Tyr:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _