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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTRA1
All Species:
26.36
Human Site:
T472
Identified Species:
52.73
UniProt:
Q92743
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92743
NP_002766.1
480
51287
T472
G
N
E
D
I
M
I
T
V
I
P
E
E
I
D
Chimpanzee
Pan troglodytes
XP_508084
598
64926
T590
G
N
E
D
I
M
I
T
V
I
P
E
E
I
D
Rhesus Macaque
Macaca mulatta
XP_001103628
481
51453
T473
G
N
E
D
I
M
I
T
V
I
P
E
E
I
D
Dog
Lupus familis
XP_535044
364
39543
V357
N
E
D
I
M
I
T
V
I
P
E
E
I
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9R118
480
51228
T472
G
N
E
D
I
V
I
T
V
I
P
E
E
I
D
Rat
Rattus norvegicus
NP_113909
480
51312
T472
G
N
E
D
I
V
I
T
V
V
P
E
E
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510536
221
23778
V214
N
E
D
I
M
I
T
V
V
P
E
E
I
D
P
Chicken
Gallus gallus
XP_420813
466
50374
N459
G
N
D
D
L
L
F
N
I
E
P
E
I
V
M
Frog
Xenopus laevis
NP_001088796
457
48812
S449
G
N
E
D
I
P
I
S
V
T
P
K
E
I
E
Zebra Danio
Brachydanio rerio
NP_001002219
479
51423
T471
G
N
E
D
I
I
L
T
I
I
P
M
E
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFJ3
422
45981
V415
R
G
V
K
Q
M
H
V
T
I
T
P
E
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3E6S8
459
49256
P452
R
V
T
L
E
V
I
P
E
E
A
N
P
D
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.9
99.1
71
N.A.
91
91.8
N.A.
44.5
57
65.6
69.7
N.A.
37
N.A.
N.A.
N.A.
Protein Similarity:
100
72
99.5
73.5
N.A.
93.9
94.5
N.A.
46
74.1
77.5
82.7
N.A.
56.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
86.6
N.A.
13.3
33.3
66.6
73.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
33.3
66.6
86.6
93.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
25
67
0
0
0
0
0
0
0
0
0
34
50
% D
% Glu:
0
17
59
0
9
0
0
0
9
17
17
67
67
0
9
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
67
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
59
25
59
0
25
50
0
0
25
59
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
0
0
9
9
9
9
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
17
34
0
0
0
0
0
9
0
0
17
% M
% Asn:
17
67
0
0
0
0
0
9
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
9
0
17
67
9
9
0
25
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
17
50
9
9
9
0
0
0
0
% T
% Val:
0
9
9
0
0
25
0
25
59
9
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _