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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFAP2C
All Species:
17.27
Human Site:
S137
Identified Species:
42.22
UniProt:
Q92754
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92754
NP_003213.1
450
49177
S137
G
L
E
A
G
A
V
S
A
R
R
D
A
Y
R
Chimpanzee
Pan troglodytes
XP_001156107
688
74356
S375
G
L
E
A
G
A
V
S
A
R
R
D
A
Y
R
Rhesus Macaque
Macaca mulatta
XP_001093748
546
59251
S233
G
L
E
A
G
A
V
S
A
R
R
D
A
Y
R
Dog
Lupus familis
XP_543065
450
49156
S137
G
L
E
G
G
A
M
S
A
R
R
D
A
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61312
449
49132
S137
G
L
E
G
G
S
V
S
A
R
R
E
V
Y
R
Rat
Rattus norvegicus
P58197
437
47928
P137
H
E
D
L
L
H
G
P
H
G
L
G
S
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514207
437
47981
P137
H
E
D
L
L
H
G
P
H
G
L
S
S
G
L
Chicken
Gallus gallus
XP_417497
448
48969
R137
S
G
S
A
G
G
R
R
E
T
F
R
R
S
D
Frog
Xenopus laevis
Q2T9K2
434
47032
H138
P
G
L
T
D
G
G
H
S
L
A
D
S
S
L
Zebra Danio
Brachydanio rerio
Q6P0E7
423
45495
H145
G
D
G
P
L
G
M
H
A
V
H
H
G
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.4
81.5
95.3
N.A.
89.1
64.4
N.A.
64.4
78.4
52.2
53.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
65.4
82
98.2
N.A.
94.2
77.3
N.A.
77.3
89.7
64.8
67.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
73.3
0
N.A.
0
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
13.3
N.A.
13.3
13.3
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
40
0
40
0
0
60
0
10
0
40
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
20
0
10
0
0
0
0
0
0
50
0
0
20
% D
% Glu:
0
20
50
0
0
0
0
0
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
60
20
10
20
60
30
30
0
0
20
0
10
10
20
0
% G
% His:
20
0
0
0
0
20
0
20
20
0
10
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
50
10
20
30
0
0
0
0
10
20
0
0
10
30
% L
% Met:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
10
0
0
0
20
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
50
50
10
10
0
50
% R
% Ser:
10
0
10
0
0
10
0
50
10
0
0
10
30
20
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
40
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _