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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TFAP2C All Species: 18.48
Human Site: S70 Identified Species: 45.19
UniProt: Q92754 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92754 NP_003213.1 450 49177 S70 P Y Q Q L A Y S Q S A D P Y S
Chimpanzee Pan troglodytes XP_001156107 688 74356 S308 P Y Q Q L A Y S Q S A D P Y S
Rhesus Macaque Macaca mulatta XP_001093748 546 59251 S166 P Y Q Q L A Y S Q S A D P Y S
Dog Lupus familis XP_543065 450 49156 S70 P Y Q Q L A Y S Q S A D P Y S
Cat Felis silvestris
Mouse Mus musculus Q61312 449 49132 S70 P Y Q Q V V Y S Q S A D H Y S
Rat Rattus norvegicus P58197 437 47928 Q70 Q P I Y P Q S Q D P Y S H V N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514207 437 47981 Q70 Q P I Y P Q S Q D P Y S H V N
Chicken Gallus gallus XP_417497 448 48969 Q70 Y Q P L P Y S Q S S D P Y S H
Frog Xenopus laevis Q2T9K2 434 47032 S71 S Y S Q S Q E S G Y P H L G D
Zebra Danio Brachydanio rerio Q6P0E7 423 45495 P78 P H L P E P Y P S L N S L H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.4 81.5 95.3 N.A. 89.1 64.4 N.A. 64.4 78.4 52.2 53.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 65.4 82 98.2 N.A. 94.2 77.3 N.A. 77.3 89.7 64.8 67.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 80 0 N.A. 0 6.6 20 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 6.6 N.A. 6.6 6.6 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 40 0 0 0 0 50 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 20 0 10 50 0 0 10 % D
% Glu: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 10 30 10 10 % H
% Ile: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 10 40 0 0 0 0 10 0 0 20 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 20 % N
% Pro: 60 20 10 10 30 10 0 10 0 20 10 10 40 0 0 % P
% Gln: 20 10 50 60 0 30 0 30 50 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 10 0 10 0 30 60 20 60 0 30 0 10 50 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 10 0 0 0 0 0 0 0 20 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 60 0 20 0 10 60 0 0 10 20 0 10 50 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _