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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H4
All Species:
13.64
Human Site:
T133
Identified Species:
30
UniProt:
Q92759
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92759
NP_001508.1
462
52186
T133
G
K
A
W
S
D
D
T
S
Q
L
G
P
D
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848919
463
52255
T134
G
K
A
W
S
D
D
T
S
Q
L
G
P
D
K
Cat
Felis silvestris
Mouse
Mus musculus
O70422
463
52206
T134
G
K
A
W
S
D
D
T
S
Q
L
G
P
D
K
Rat
Rattus norvegicus
NP_997666
463
52193
T134
G
K
A
W
S
D
D
T
S
Q
L
G
P
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513954
472
52374
V133
Q
P
L
P
Q
A
A
V
A
L
W
V
K
K
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085110
455
51896
D126
G
G
K
A
W
A
D
D
G
C
L
L
G
P
D
Zebra Danio
Brachydanio rerio
NP_956221
466
52671
E125
G
G
K
P
W
A
D
E
G
A
N
L
G
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648780
499
56633
K156
P
M
T
N
T
L
D
K
D
S
K
P
R
D
I
Honey Bee
Apis mellifera
XP_395476
467
53265
N135
G
K
P
W
T
M
S
N
Q
L
E
T
D
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796111
469
52883
K138
A
I
S
G
K
G
G
K
G
G
K
D
K
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02939
513
58516
F121
G
G
E
V
Q
N
S
F
G
V
V
V
E
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
98.9
N.A.
98.6
98.9
N.A.
58.2
N.A.
83.1
77.9
N.A.
49
57.5
N.A.
57.5
Protein Similarity:
100
N.A.
N.A.
99.3
N.A.
99.1
99.3
N.A.
64.4
N.A.
90.9
87.1
N.A.
65.9
74
N.A.
76.3
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
N.A.
20
13.3
N.A.
13.3
26.6
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
13.3
N.A.
20
13.3
N.A.
20
33.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
37
10
0
28
10
0
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
37
64
10
10
0
0
10
10
46
19
% D
% Glu:
0
0
10
0
0
0
0
10
0
0
10
0
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
73
28
0
10
0
10
10
0
37
10
0
37
19
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
46
19
0
10
0
0
19
0
0
19
0
19
19
46
% K
% Leu:
0
0
10
0
0
10
0
0
0
19
46
19
0
0
0
% L
% Met:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
10
0
0
10
0
0
0
10
% N
% Pro:
10
10
10
19
0
0
0
0
0
0
0
10
37
19
0
% P
% Gln:
10
0
0
0
19
0
0
0
10
37
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
10
0
37
0
19
0
37
10
0
0
0
10
0
% S
% Thr:
0
0
10
0
19
0
0
37
0
0
0
10
0
0
0
% T
% Val:
0
0
0
10
0
0
0
10
0
10
10
19
0
0
10
% V
% Trp:
0
0
0
46
19
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _