Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2H4 All Species: 40
Human Site: T244 Identified Species: 88
UniProt: Q92759 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92759 NP_001508.1 462 52186 T244 L F Q L S F S T L G K D Y S V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848919 463 52255 T245 L F Q L S F S T L G K D Y S V
Cat Felis silvestris
Mouse Mus musculus O70422 463 52206 T245 L F Q L S F S T L G K D Y S V
Rat Rattus norvegicus NP_997666 463 52193 T245 L F Q L S F S T L G K D Y S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513954 472 52374 T244 L F Q L S F S T L G K D Y S V
Chicken Gallus gallus
Frog Xenopus laevis NP_001085110 455 51896 T237 M F Q L S F S T L G K D Y S V
Zebra Danio Brachydanio rerio NP_956221 466 52671 T236 L F Q L S F S T L G R D Y S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648780 499 56633 T267 L F Q L S F S T L G R D Y S S
Honey Bee Apis mellifera XP_395476 467 53265 T246 L F Q L N F S T L G K D Y S T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796111 469 52883 T249 L F Q L S F S T L G K D Y S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02939 513 58516 E232 I F M L G A L E V G K A Y K I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 98.9 N.A. 98.6 98.9 N.A. 58.2 N.A. 83.1 77.9 N.A. 49 57.5 N.A. 57.5
Protein Similarity: 100 N.A. N.A. 99.3 N.A. 99.1 99.3 N.A. 64.4 N.A. 90.9 87.1 N.A. 65.9 74 N.A. 76.3
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 86.6 86.6 N.A. 93.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 56.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 91 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 100 0 0 0 91 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 0 100 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 82 0 0 10 0 % K
% Leu: 82 0 0 100 0 0 10 0 91 0 0 0 0 0 0 % L
% Met: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 91 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % R
% Ser: 0 0 0 0 82 0 91 0 0 0 0 0 0 91 19 % S
% Thr: 0 0 0 0 0 0 0 91 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 64 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _