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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2H4 All Species: 15.15
Human Site: Y151 Identified Species: 33.33
UniProt: Q92759 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92759 NP_001508.1 462 52186 Y151 D V P S L D K Y A E E R W E V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848919 463 52255 Y152 D V P S L D K Y A E E R W E V
Cat Felis silvestris
Mouse Mus musculus O70422 463 52206 Y152 D V P S L D K Y A E E R W E V
Rat Rattus norvegicus NP_997666 463 52193 Y152 D V P S L D K Y A E E R W E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513954 472 52374 L151 A Q E E S T G L L S R L R L W
Chicken Gallus gallus
Frog Xenopus laevis NP_001085110 455 51896 K144 K D V V S L D K Y A E E R W E
Zebra Danio Brachydanio rerio NP_956221 466 52671 R143 R D V E S L D R Y A M E R W E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648780 499 56633 W174 D T Y A M S R W R C V L H Y M
Honey Bee Apis mellifera XP_395476 467 53265 A153 V A F L D S Y A L E R W E C V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796111 469 52883 S156 A T L D K Y S S E R W E C V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02939 513 58516 S139 L D L L D E Y S A N K W E T I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 98.9 N.A. 98.6 98.9 N.A. 58.2 N.A. 83.1 77.9 N.A. 49 57.5 N.A. 57.5
Protein Similarity: 100 N.A. N.A. 99.3 N.A. 99.1 99.3 N.A. 64.4 N.A. 90.9 87.1 N.A. 65.9 74 N.A. 76.3
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 N.A. 6.6 0 N.A. 6.6 13.3 N.A. 0
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 N.A. 6.6 0 N.A. 40 13.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 56.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 0 10 0 0 0 10 46 19 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 10 10 0 % C
% Asp: 46 28 0 10 19 37 19 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 19 0 10 0 0 10 46 46 28 19 37 19 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 10 0 0 0 10 0 37 10 0 0 10 0 0 0 0 % K
% Leu: 10 0 19 19 37 19 0 10 19 0 0 19 0 10 10 % L
% Met: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 10 10 10 10 19 37 28 0 0 % R
% Ser: 0 0 0 37 28 19 10 19 0 10 0 0 0 0 0 % S
% Thr: 0 19 0 0 0 10 0 0 0 0 0 0 0 10 0 % T
% Val: 10 37 19 10 0 0 0 0 0 0 10 0 0 10 46 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 10 19 37 19 10 % W
% Tyr: 0 0 10 0 0 10 19 37 19 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _