Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2H4 All Species: 28.48
Human Site: Y281 Identified Species: 62.67
UniProt: Q92759 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92759 NP_001508.1 462 52186 Y281 R K R K S R R Y Y P T R L A I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848919 463 52255 Y282 R K R K S R R Y Y P T R L A I
Cat Felis silvestris
Mouse Mus musculus O70422 463 52206 Y282 R K R K S R R Y Y P T R L A I
Rat Rattus norvegicus NP_997666 463 52193 Y282 R K R K S R R Y Y P T R L A I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513954 472 52374 Y281 R K R K S R R Y Y P T R L A I
Chicken Gallus gallus
Frog Xenopus laevis NP_001085110 455 51896 Y274 R K R K S R R Y Y P T R L A I
Zebra Danio Brachydanio rerio NP_956221 466 52671 G285 L A I T L A A G V T A N P A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648780 499 56633 L311 F Y P T R L A L N V T S K E A
Honey Bee Apis mellifera XP_395476 467 53265 Y284 K R K A G R F Y P T R L A L N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796111 469 52883 Y286 R K R K S M R Y Y P T R L A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02939 513 58516 K313 N E D G A N G K S T T D I T T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 98.9 N.A. 98.6 98.9 N.A. 58.2 N.A. 83.1 77.9 N.A. 49 57.5 N.A. 57.5
Protein Similarity: 100 N.A. N.A. 99.3 N.A. 99.1 99.3 N.A. 64.4 N.A. 90.9 87.1 N.A. 65.9 74 N.A. 76.3
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 N.A. 100 6.6 N.A. 6.6 13.3 N.A. 93.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 N.A. 100 6.6 N.A. 6.6 33.3 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 56.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 10 10 19 0 0 0 10 0 10 73 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % E
% Phe: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 10 0 10 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 64 % I
% Lys: 10 64 10 64 0 0 0 10 0 0 0 0 10 0 0 % K
% Leu: 10 0 0 0 10 10 0 10 0 0 0 10 64 10 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 10 0 0 10 0 0 10 0 0 10 % N
% Pro: 0 0 10 0 0 0 0 0 10 64 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 64 10 64 0 10 64 64 0 0 0 10 64 0 0 0 % R
% Ser: 0 0 0 0 64 0 0 0 10 0 0 10 0 0 10 % S
% Thr: 0 0 0 19 0 0 0 0 0 28 82 0 0 10 10 % T
% Val: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 73 64 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _