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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H4
All Species:
28.48
Human Site:
Y281
Identified Species:
62.67
UniProt:
Q92759
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92759
NP_001508.1
462
52186
Y281
R
K
R
K
S
R
R
Y
Y
P
T
R
L
A
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848919
463
52255
Y282
R
K
R
K
S
R
R
Y
Y
P
T
R
L
A
I
Cat
Felis silvestris
Mouse
Mus musculus
O70422
463
52206
Y282
R
K
R
K
S
R
R
Y
Y
P
T
R
L
A
I
Rat
Rattus norvegicus
NP_997666
463
52193
Y282
R
K
R
K
S
R
R
Y
Y
P
T
R
L
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513954
472
52374
Y281
R
K
R
K
S
R
R
Y
Y
P
T
R
L
A
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085110
455
51896
Y274
R
K
R
K
S
R
R
Y
Y
P
T
R
L
A
I
Zebra Danio
Brachydanio rerio
NP_956221
466
52671
G285
L
A
I
T
L
A
A
G
V
T
A
N
P
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648780
499
56633
L311
F
Y
P
T
R
L
A
L
N
V
T
S
K
E
A
Honey Bee
Apis mellifera
XP_395476
467
53265
Y284
K
R
K
A
G
R
F
Y
P
T
R
L
A
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796111
469
52883
Y286
R
K
R
K
S
M
R
Y
Y
P
T
R
L
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02939
513
58516
K313
N
E
D
G
A
N
G
K
S
T
T
D
I
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
98.9
N.A.
98.6
98.9
N.A.
58.2
N.A.
83.1
77.9
N.A.
49
57.5
N.A.
57.5
Protein Similarity:
100
N.A.
N.A.
99.3
N.A.
99.1
99.3
N.A.
64.4
N.A.
90.9
87.1
N.A.
65.9
74
N.A.
76.3
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
N.A.
100
6.6
N.A.
6.6
13.3
N.A.
93.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
N.A.
100
6.6
N.A.
6.6
33.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
10
19
0
0
0
10
0
10
73
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
0
10
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
64
% I
% Lys:
10
64
10
64
0
0
0
10
0
0
0
0
10
0
0
% K
% Leu:
10
0
0
0
10
10
0
10
0
0
0
10
64
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
10
0
0
10
0
0
10
0
0
10
% N
% Pro:
0
0
10
0
0
0
0
0
10
64
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
64
10
64
0
10
64
64
0
0
0
10
64
0
0
0
% R
% Ser:
0
0
0
0
64
0
0
0
10
0
0
10
0
0
10
% S
% Thr:
0
0
0
19
0
0
0
0
0
28
82
0
0
10
10
% T
% Val:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
73
64
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _