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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2H4 All Species: 39.39
Human Site: Y409 Identified Species: 86.67
UniProt: Q92759 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92759 NP_001508.1 462 52186 Y409 R F T E G V L Y N Q F L S Q V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848919 463 52255 Y410 R F T E G V L Y N Q F L S Q V
Cat Felis silvestris
Mouse Mus musculus O70422 463 52206 Y410 R F T E G V L Y N Q F L S Q V
Rat Rattus norvegicus NP_997666 463 52193 Y410 R F T E G V L Y N Q F L S Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513954 472 52374 Y419 R G G G G V L Y N Q F L S Q V
Chicken Gallus gallus
Frog Xenopus laevis NP_001085110 455 51896 Y402 R F S E G V L Y N Q F L S Q V
Zebra Danio Brachydanio rerio NP_956221 466 52671 Y413 Q F T E G V L Y N Q F L S Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648780 499 56633 Y445 T Y T E G V L Y N Q F L S H T
Honey Bee Apis mellifera XP_395476 467 53265 Y413 I F S E G V L Y S Q F L S Q T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796111 469 52883 Y414 S F T Q G I I Y N E F L S L H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02939 513 58516 Y459 I T Y E G S L Y S D F E T S Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 98.9 N.A. 98.6 98.9 N.A. 58.2 N.A. 83.1 77.9 N.A. 49 57.5 N.A. 57.5
Protein Similarity: 100 N.A. N.A. 99.3 N.A. 99.1 99.3 N.A. 64.4 N.A. 90.9 87.1 N.A. 65.9 74 N.A. 76.3
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 80 N.A. 93.3 86.6 N.A. 73.3 73.3 N.A. 53.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 80 N.A. 100 93.3 N.A. 80 86.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 56.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 82 0 0 0 0 0 10 0 10 0 0 0 % E
% Phe: 0 73 0 0 0 0 0 0 0 0 100 0 0 0 0 % F
% Gly: 0 10 10 10 100 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % H
% Ile: 19 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 91 0 0 0 0 91 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 82 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 10 0 0 0 0 0 82 0 0 0 73 10 % Q
% Arg: 55 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 19 0 0 10 0 0 19 0 0 0 91 10 0 % S
% Thr: 10 10 64 0 0 0 0 0 0 0 0 0 10 0 19 % T
% Val: 0 0 0 0 0 82 0 0 0 0 0 0 0 0 55 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _