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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRZB
All Species:
16.36
Human Site:
S226
Identified Species:
32.73
UniProt:
Q92765
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92765
NP_001454.2
325
36254
S226
V
K
E
I
L
K
S
S
L
V
N
I
P
R
D
Chimpanzee
Pan troglodytes
XP_001170319
353
40092
I237
I
F
K
S
S
S
P
I
P
R
T
Q
V
P
L
Rhesus Macaque
Macaca mulatta
Q7YRN1
346
39750
S226
D
V
K
E
I
F
K
S
S
S
P
I
P
R
T
Dog
Lupus familis
XP_856560
339
38675
S219
D
V
K
E
I
F
K
S
L
S
P
I
P
R
T
Cat
Felis silvestris
Mouse
Mus musculus
P97401
323
35992
S226
V
K
E
I
L
K
A
S
L
V
N
I
P
R
D
Rat
Rattus norvegicus
Q9JLS4
348
39744
S226
D
V
K
E
I
F
K
S
S
S
P
I
P
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515723
212
24543
T125
L
V
S
I
P
K
D
T
V
N
L
Y
T
N
S
Chicken
Gallus gallus
Q9IA95
315
34985
S218
V
K
E
I
L
K
S
S
L
V
N
I
P
K
D
Frog
Xenopus laevis
Q8AVJ9
548
61888
C385
G
D
V
L
S
G
V
C
Y
V
G
I
N
S
V
Zebra Danio
Brachydanio rerio
NP_571018
315
36013
N222
V
K
E
I
R
I
R
N
H
D
L
S
A
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
C470
G
D
P
I
L
G
I
C
Y
V
G
N
L
N
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786860
267
30741
V180
F
S
E
I
H
I
P
V
G
E
V
Q
L
W
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.4
48.5
50.4
N.A.
91.3
49.4
N.A.
46.1
81.5
23.1
65.8
N.A.
21
N.A.
N.A.
38.4
Protein Similarity:
100
66.2
66.1
67.8
N.A.
96
67.5
N.A.
54.1
88
36.5
79.6
N.A.
31.2
N.A.
N.A.
52.9
P-Site Identity:
100
0
26.6
33.3
N.A.
93.3
26.6
N.A.
13.3
93.3
13.3
26.6
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
40
46.6
N.A.
100
40
N.A.
33.3
100
20
33.3
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
25
17
0
0
0
0
9
0
0
9
0
0
0
0
25
% D
% Glu:
0
0
42
25
0
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
9
9
0
0
0
25
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
17
0
0
9
0
17
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
9
0
0
59
25
17
9
9
0
0
0
59
0
9
0
% I
% Lys:
0
34
34
0
0
34
25
0
0
0
0
0
0
9
0
% K
% Leu:
9
0
0
9
34
0
0
0
34
0
17
0
17
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
9
25
9
9
17
0
% N
% Pro:
0
0
9
0
9
0
17
0
9
0
25
0
50
9
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% Q
% Arg:
0
0
0
0
9
0
9
0
0
9
0
0
0
42
0
% R
% Ser:
0
9
9
9
17
9
17
50
17
25
0
9
0
9
9
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
9
0
9
0
25
% T
% Val:
34
34
9
0
0
0
9
9
9
42
9
0
9
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
17
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _