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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRZB
All Species:
9.09
Human Site:
S273
Identified Species:
18.18
UniProt:
Q92765
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92765
NP_001454.2
325
36254
S273
R
L
L
L
V
E
G
S
I
A
E
K
W
K
D
Chimpanzee
Pan troglodytes
XP_001170319
353
40092
R284
N
C
L
V
E
K
W
R
D
Q
L
S
K
R
S
Rhesus Macaque
Macaca mulatta
Q7YRN1
346
39750
V273
M
L
L
E
N
C
L
V
E
K
W
R
D
Q
L
Dog
Lupus familis
XP_856560
339
38675
V266
M
L
L
E
N
C
L
V
E
K
W
R
D
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
P97401
323
35992
S273
R
L
L
L
V
E
G
S
I
A
E
K
W
K
D
Rat
Rattus norvegicus
Q9JLS4
348
39744
V273
M
L
L
E
N
C
L
V
E
K
W
R
D
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515723
212
24543
R172
I
A
E
K
W
K
D
R
L
G
K
K
V
K
R
Chicken
Gallus gallus
Q9IA95
315
34985
S265
R
L
L
L
V
E
G
S
I
A
E
K
W
K
D
Frog
Xenopus laevis
Q8AVJ9
548
61888
G432
R
T
I
M
K
H
D
G
T
K
T
E
K
L
E
Zebra Danio
Brachydanio rerio
NP_571018
315
36013
M269
A
N
D
E
Y
I
I
M
G
Y
E
N
E
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
G517
R
S
V
I
K
Q
Q
G
G
V
G
A
G
V
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786860
267
30741
H227
D
C
L
V
I
P
W
H
S
R
Y
V
K
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.4
48.5
50.4
N.A.
91.3
49.4
N.A.
46.1
81.5
23.1
65.8
N.A.
21
N.A.
N.A.
38.4
Protein Similarity:
100
66.2
66.1
67.8
N.A.
96
67.5
N.A.
54.1
88
36.5
79.6
N.A.
31.2
N.A.
N.A.
52.9
P-Site Identity:
100
6.6
13.3
13.3
N.A.
100
13.3
N.A.
13.3
100
6.6
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
26.6
26.6
N.A.
100
26.6
N.A.
33.3
100
33.3
13.3
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
0
0
25
0
9
0
0
0
% A
% Cys:
0
17
0
0
0
25
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
17
0
9
0
0
0
25
0
25
% D
% Glu:
0
0
9
34
9
25
0
0
25
0
34
9
9
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
25
17
17
9
9
0
9
0
0
% G
% His:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
9
9
9
9
0
25
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
17
17
0
0
0
34
9
34
25
34
9
% K
% Leu:
0
50
67
25
0
0
25
0
9
0
9
0
0
9
25
% L
% Met:
25
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
25
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
9
0
0
9
0
0
0
25
0
% Q
% Arg:
42
0
0
0
0
0
0
17
0
9
0
25
0
17
17
% R
% Ser:
0
9
0
0
0
0
0
25
9
0
0
9
0
0
9
% S
% Thr:
0
9
0
0
0
0
0
0
9
0
9
0
0
0
0
% T
% Val:
0
0
9
17
25
0
0
25
0
9
0
9
9
9
9
% V
% Trp:
0
0
0
0
9
0
17
0
0
0
25
0
25
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
9
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _