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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRZB
All Species:
4.55
Human Site:
S311
Identified Species:
9.09
UniProt:
Q92765
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92765
NP_001454.2
325
36254
S311
S
N
S
D
S
T
Q
S
Q
K
S
G
R
N
S
Chimpanzee
Pan troglodytes
XP_001170319
353
40092
K326
N
P
P
K
P
K
G
K
P
P
A
P
K
P
T
Rhesus Macaque
Macaca mulatta
Q7YRN1
346
39750
K319
N
P
P
K
P
K
G
K
P
P
A
P
K
P
A
Dog
Lupus familis
XP_856560
339
38675
P309
S
R
S
N
T
P
K
P
K
G
K
P
P
A
P
Cat
Felis silvestris
Mouse
Mus musculus
P97401
323
35992
N309
D
A
S
D
S
T
Q
N
Q
K
S
G
R
N
S
Rat
Rattus norvegicus
Q9JLS4
348
39744
A334
S
P
K
K
N
I
K
A
R
S
A
P
K
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515723
212
24543
S199
N
E
P
E
Q
S
E
S
A
Q
K
S
G
K
N
Chicken
Gallus gallus
Q9IA95
315
34985
A301
E
P
G
Q
S
D
S
A
L
K
T
G
K
P
G
Frog
Xenopus laevis
Q8AVJ9
548
61888
S524
T
S
S
F
W
I
W
S
G
K
T
L
Q
S
W
Zebra Danio
Brachydanio rerio
NP_571018
315
36013
V298
K
E
K
I
G
R
K
V
K
R
W
D
Q
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
H678
A
S
V
A
S
T
S
H
H
H
L
H
H
H
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786860
267
30741
R254
D
R
D
S
S
D
S
R
S
N
R
R
N
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.4
48.5
50.4
N.A.
91.3
49.4
N.A.
46.1
81.5
23.1
65.8
N.A.
21
N.A.
N.A.
38.4
Protein Similarity:
100
66.2
66.1
67.8
N.A.
96
67.5
N.A.
54.1
88
36.5
79.6
N.A.
31.2
N.A.
N.A.
52.9
P-Site Identity:
100
0
0
13.3
N.A.
80
13.3
N.A.
6.6
20
20
0
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
26.6
40
N.A.
86.6
53.3
N.A.
46.6
40
53.3
33.3
N.A.
33.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
0
0
17
9
0
25
0
0
17
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
9
17
0
17
0
0
0
0
0
9
0
0
9
% D
% Glu:
9
17
0
9
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
9
0
17
0
9
9
0
25
9
0
9
% G
% His:
0
0
0
0
0
0
0
9
9
9
0
9
9
9
0
% H
% Ile:
0
0
0
9
0
17
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
17
25
0
17
25
17
17
34
17
0
34
17
0
% K
% Leu:
0
0
0
0
0
0
0
0
9
0
9
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
25
9
0
9
9
0
0
9
0
9
0
0
9
17
9
% N
% Pro:
0
34
25
0
17
9
0
9
17
17
0
34
9
25
9
% P
% Gln:
0
0
0
9
9
0
17
0
17
9
0
0
17
0
0
% Q
% Arg:
0
17
0
0
0
9
0
9
9
9
9
9
17
9
0
% R
% Ser:
25
17
34
9
42
9
25
25
9
9
17
9
0
9
25
% S
% Thr:
9
0
0
0
9
25
0
0
0
0
17
0
0
0
9
% T
% Val:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
9
0
9
0
0
0
9
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _