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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRZB
All Species:
17.27
Human Site:
Y195
Identified Species:
34.55
UniProt:
Q92765
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92765
NP_001454.2
325
36254
Y195
K
T
Y
F
R
N
N
Y
N
Y
V
I
R
A
K
Chimpanzee
Pan troglodytes
XP_001170319
353
40092
I206
S
K
N
Y
S
Y
V
I
H
A
K
I
K
A
V
Rhesus Macaque
Macaca mulatta
Q7YRN1
346
39750
C195
A
T
Y
L
S
K
N
C
S
Y
V
I
H
A
K
Dog
Lupus familis
XP_856560
339
38675
Y188
A
T
Y
L
S
K
N
Y
S
Y
V
I
H
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P97401
323
35992
Y195
K
T
Y
F
R
N
N
Y
N
Y
V
I
R
A
K
Rat
Rattus norvegicus
Q9JLS4
348
39744
Y195
A
T
Y
L
S
K
N
Y
S
Y
V
I
H
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515723
212
24543
V94
N
Y
V
I
R
A
K
V
K
E
I
K
A
R
C
Chicken
Gallus gallus
Q9IA95
315
34985
Y187
K
T
Y
L
R
N
N
Y
N
Y
V
I
R
A
K
Frog
Xenopus laevis
Q8AVJ9
548
61888
Y354
A
I
E
A
N
S
Q
Y
F
H
L
A
A
W
A
Zebra Danio
Brachydanio rerio
NP_571018
315
36013
K191
K
G
A
N
D
R
C
K
C
K
S
V
K
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
Y439
A
I
T
K
H
S
Q
Y
F
H
L
A
A
W
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786860
267
30741
V149
P
T
V
I
R
A
R
V
E
G
F
H
S
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.4
48.5
50.4
N.A.
91.3
49.4
N.A.
46.1
81.5
23.1
65.8
N.A.
21
N.A.
N.A.
38.4
Protein Similarity:
100
66.2
66.1
67.8
N.A.
96
67.5
N.A.
54.1
88
36.5
79.6
N.A.
31.2
N.A.
N.A.
52.9
P-Site Identity:
100
13.3
53.3
60
N.A.
100
60
N.A.
6.6
93.3
6.6
6.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
33.3
60
66.6
N.A.
100
66.6
N.A.
13.3
93.3
26.6
20
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
9
9
0
17
0
0
0
9
0
17
25
59
9
% A
% Cys:
0
0
0
0
0
0
9
9
9
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
9
9
0
0
0
0
0
% E
% Phe:
0
0
0
17
0
0
0
0
17
0
9
0
0
9
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
9
0
0
0
9
0
% G
% His:
0
0
0
0
9
0
0
0
9
17
0
9
25
0
0
% H
% Ile:
0
17
0
17
0
0
0
9
0
0
9
59
0
0
0
% I
% Lys:
34
9
0
9
0
25
9
9
9
9
9
9
17
0
50
% K
% Leu:
0
0
0
34
0
0
0
0
0
0
17
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
9
9
25
50
0
25
0
0
0
0
0
9
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
42
9
9
0
0
0
0
0
25
9
0
% R
% Ser:
9
0
0
0
34
17
0
0
25
0
9
0
9
0
0
% S
% Thr:
0
59
9
0
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
0
17
0
0
0
9
17
0
0
50
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% W
% Tyr:
0
9
50
9
0
9
0
59
0
50
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _