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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRZB
All Species:
10
Human Site:
Y238
Identified Species:
20
UniProt:
Q92765
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92765
NP_001454.2
325
36254
Y238
P
R
D
T
V
N
L
Y
T
S
S
G
C
L
C
Chimpanzee
Pan troglodytes
XP_001170319
353
40092
S249
V
P
L
I
T
N
S
S
C
Q
C
P
H
I
L
Rhesus Macaque
Macaca mulatta
Q7YRN1
346
39750
I238
P
R
T
Q
V
P
L
I
T
N
S
S
C
Q
C
Dog
Lupus familis
XP_856560
339
38675
I231
P
R
T
Q
V
P
L
I
T
N
S
S
C
Q
C
Cat
Felis silvestris
Mouse
Mus musculus
P97401
323
35992
Y238
P
R
D
T
V
N
L
Y
T
T
S
G
C
L
C
Rat
Rattus norvegicus
Q9JLS4
348
39744
I238
P
R
T
Q
V
P
L
I
T
N
S
S
C
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515723
212
24543
P137
T
N
S
A
C
L
C
P
P
L
A
A
N
E
E
Chicken
Gallus gallus
Q9IA95
315
34985
Y230
P
K
D
T
V
N
L
Y
T
N
S
G
C
L
C
Frog
Xenopus laevis
Q8AVJ9
548
61888
G397
N
S
V
D
S
L
R
G
F
V
L
A
P
L
F
Zebra Danio
Brachydanio rerio
NP_571018
315
36013
V234
A
I
V
E
V
K
E
V
L
K
S
S
L
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
T482
L
N
P
D
H
L
K
T
F
V
L
A
P
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786860
267
30741
A192
L
W
V
N
N
Y
C
A
C
P
M
M
T
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.4
48.5
50.4
N.A.
91.3
49.4
N.A.
46.1
81.5
23.1
65.8
N.A.
21
N.A.
N.A.
38.4
Protein Similarity:
100
66.2
66.1
67.8
N.A.
96
67.5
N.A.
54.1
88
36.5
79.6
N.A.
31.2
N.A.
N.A.
52.9
P-Site Identity:
100
6.6
53.3
53.3
N.A.
93.3
53.3
N.A.
0
86.6
6.6
13.3
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
13.3
60
60
N.A.
100
60
N.A.
6.6
100
6.6
20
N.A.
6.6
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
0
9
0
0
9
25
0
0
0
% A
% Cys:
0
0
0
0
9
0
17
0
17
0
9
0
50
0
50
% C
% Asp:
0
0
25
17
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
9
0
0
0
0
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
17
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
25
0
0
9
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
9
0
9
0
0
0
25
0
0
0
0
0
9
0
% I
% Lys:
0
9
0
0
0
9
9
0
0
9
0
0
0
0
0
% K
% Leu:
17
0
9
0
0
25
50
0
9
9
17
0
9
42
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
9
17
0
9
9
34
0
0
0
34
0
0
9
0
9
% N
% Pro:
50
9
9
0
0
25
0
9
9
9
0
9
17
0
0
% P
% Gln:
0
0
0
25
0
0
0
0
0
9
0
0
0
25
0
% Q
% Arg:
0
42
0
0
0
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
9
0
9
0
9
9
0
9
59
34
0
9
0
% S
% Thr:
9
0
25
25
9
0
0
9
50
9
0
0
9
0
0
% T
% Val:
9
0
25
0
59
0
0
9
0
17
0
0
0
9
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
25
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _