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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRZB All Species: 9.7
Human Site: Y254 Identified Species: 19.39
UniProt: Q92765 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92765 NP_001454.2 325 36254 Y254 P L N V N E E Y I I M G Y E D
Chimpanzee Pan troglodytes XP_001170319 353 40092 C265 H Q D V L I M C Y E W R S R M
Rhesus Macaque Macaca mulatta Q7YRN1 346 39750 V254 H I L P H Q D V L I M C Y E W
Dog Lupus familis XP_856560 339 38675 V247 H I L P H Q D V L I M C Y E W
Cat Felis silvestris
Mouse Mus musculus P97401 323 35992 Y254 P L T V N E E Y V I M G Y E D
Rat Rattus norvegicus Q9JLS4 348 39744 V254 H I L P H Q D V L I M C Y E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515723 212 24543 E153 I I M G Y E D E E R S R L L L
Chicken Gallus gallus Q9IA95 315 34985 Y246 P L S A N E E Y I I M G Y E D
Frog Xenopus laevis Q8AVJ9 548 61888 F413 Y L F L G T S F L L A G F V S
Zebra Danio Brachydanio rerio NP_571018 315 36013 Y250 P R D T V T L Y Y N S G C L C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVX3 694 75433 F498 Y L V I G T T F L M A G F V S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786860 267 30741 Q208 E Y M I M C Y Q D I I N G R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.4 48.5 50.4 N.A. 91.3 49.4 N.A. 46.1 81.5 23.1 65.8 N.A. 21 N.A. N.A. 38.4
Protein Similarity: 100 66.2 66.1 67.8 N.A. 96 67.5 N.A. 54.1 88 36.5 79.6 N.A. 31.2 N.A. N.A. 52.9
P-Site Identity: 100 6.6 26.6 26.6 N.A. 86.6 26.6 N.A. 6.6 86.6 13.3 20 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 13.3 60 60 N.A. 93.3 60 N.A. 20 93.3 46.6 26.6 N.A. 46.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 0 17 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 9 0 0 0 25 9 0 9 % C
% Asp: 0 0 17 0 0 0 34 0 9 0 0 0 0 0 25 % D
% Glu: 9 0 0 0 0 34 25 9 9 9 0 0 0 50 0 % E
% Phe: 0 0 9 0 0 0 0 17 0 0 0 0 17 0 0 % F
% Gly: 0 0 0 9 17 0 0 0 0 0 0 50 9 0 0 % G
% His: 34 0 0 0 25 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 34 0 17 0 9 0 0 17 59 9 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 42 25 9 9 0 9 0 42 9 0 0 9 17 17 % L
% Met: 0 0 17 0 9 0 9 0 0 9 50 0 0 0 9 % M
% Asn: 0 0 9 0 25 0 0 0 0 9 0 9 0 0 0 % N
% Pro: 34 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 25 0 9 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 0 0 0 0 0 0 9 0 17 0 17 9 % R
% Ser: 0 0 9 0 0 0 9 0 0 0 17 0 9 0 17 % S
% Thr: 0 0 9 9 0 25 9 0 0 0 0 0 0 0 0 % T
% Val: 0 0 9 25 9 0 0 25 9 0 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 17 % W
% Tyr: 17 9 0 0 9 0 9 34 17 0 0 0 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _