KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC2
All Species:
18.7
Human Site:
S482
Identified Species:
29.39
UniProt:
Q92769
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92769
NP_001518.2
488
55364
S482
T
D
T
K
G
T
K
S
E
Q
L
S
N
P
_
Chimpanzee
Pan troglodytes
XP_518700
581
65611
S575
T
D
T
K
G
T
K
S
E
Q
L
S
N
P
_
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532270
481
54585
S475
T
D
T
K
G
A
K
S
E
Q
L
S
N
P
_
Cat
Felis silvestris
Mouse
Mus musculus
P70288
488
55284
S482
T
D
P
K
G
A
K
S
E
Q
L
S
N
P
_
Rat
Rattus norvegicus
Q4QQW4
482
55074
A472
T
K
E
E
K
P
E
A
K
G
V
K
E
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521848
455
51607
K448
A
R
I
E
E
D
K
K
E
T
E
D
K
K
A
Chicken
Gallus gallus
P56519
488
55134
S482
T
D
T
K
G
A
K
S
E
Q
L
S
N
P
_
Frog
Xenopus laevis
O42227
480
54874
Zebra Danio
Brachydanio rerio
Q803C3
428
48962
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94517
521
58312
T481
E
E
S
T
A
S
N
T
N
S
N
N
N
S
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17695
461
52119
Sea Urchin
Strong. purpuratus
P56518
576
64060
A471
S
S
D
A
S
K
E
A
K
P
A
A
E
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P56521
513
57528
Q506
S
S
T
K
L
Q
G
Q
A
A
A
Y
H
K
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FML2
471
52633
E463
E
M
D
D
D
N
P
E
P
D
V
N
P
P
S
Baker's Yeast
Sacchar. cerevisiae
P32561
433
48886
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
N.A.
96.5
N.A.
99.3
85.8
N.A.
90.7
98.1
87.6
52.6
N.A.
73.3
N.A.
58.8
69.1
Protein Similarity:
100
83.9
N.A.
97.3
N.A.
99.3
93.6
N.A.
91.1
98.1
94.4
70.6
N.A.
81.9
N.A.
76
78.4
P-Site Identity:
100
100
N.A.
92.8
N.A.
85.7
6.6
N.A.
13.3
92.8
0
0
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
N.A.
92.8
N.A.
85.7
40
N.A.
20
92.8
0
0
N.A.
40
N.A.
0
40
Percent
Protein Identity:
N.A.
53.6
N.A.
56.3
53.8
N.A.
Protein Similarity:
N.A.
70.5
N.A.
72.3
69.4
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
20
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
7
20
0
14
7
7
14
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
34
14
7
7
7
0
0
0
7
0
7
0
0
0
% D
% Glu:
14
7
7
14
7
0
14
7
40
0
7
0
14
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
34
0
7
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
7
0
40
7
7
40
7
14
0
0
7
7
14
0
% K
% Leu:
0
0
0
0
7
0
0
0
0
0
34
0
0
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
7
0
7
0
7
14
40
0
7
% N
% Pro:
0
0
7
0
0
7
7
0
7
7
0
0
7
47
7
% P
% Gln:
0
0
0
0
0
7
0
7
0
34
0
0
0
0
7
% Q
% Arg:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
14
14
7
0
7
7
0
34
0
7
0
34
0
7
7
% S
% Thr:
40
0
34
7
0
14
0
7
0
7
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% _