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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYN2 All Species: 25.76
Human Site: S12 Identified Species: 62.96
UniProt: Q92777 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92777 NP_598328 582 62847 S12 L R R R L S D S S F I A N L P
Chimpanzee Pan troglodytes XP_001171832 699 75941 D136 F L R R R L S D S S F I A N L
Rhesus Macaque Macaca mulatta XP_001086745 582 63133 S12 L R R R L S D S S F I A N L P
Dog Lupus familis XP_541766 652 70650 S84 L F T K Y L L S T Y Y G P G T
Cat Felis silvestris
Mouse Mus musculus Q64332 586 63354 S12 L R R R L S D S S F I A N L P
Rat Rattus norvegicus Q63537 586 63438 S12 L R R R L S D S S F I A N L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510384 582 63180 S11 L R R R L S D S S F V A N L P
Chicken Gallus gallus
Frog Xenopus laevis NP_001079204 580 63774 S11 L R R R L S D S S F V A N L P
Zebra Danio Brachydanio rerio NP_001002597 463 51072
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24546 1025 107509 S21 V D D V D P N S L P P A A R P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.8 97.7 82.5 N.A. 93.6 93 N.A. 58.5 N.A. 61.1 53.2 N.A. 26.8 N.A. N.A. N.A.
Protein Similarity: 100 80.8 97.7 84.5 N.A. 95.5 95 N.A. 71.1 N.A. 72.6 66.8 N.A. 37.9 N.A. N.A. N.A.
P-Site Identity: 100 20 100 13.3 N.A. 100 100 N.A. 93.3 N.A. 93.3 0 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 20 100 33.3 N.A. 100 100 N.A. 100 N.A. 100 0 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 70 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 10 0 60 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 10 0 0 0 0 0 0 0 60 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 40 10 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 70 10 0 0 60 20 10 0 10 0 0 0 0 60 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 60 10 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 10 10 0 10 0 70 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 60 70 70 10 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 0 0 60 10 80 70 10 0 0 0 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 10 % T
% Val: 10 0 0 10 0 0 0 0 0 0 20 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _