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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYN2 All Species: 16.67
Human Site: T505 Identified Species: 40.74
UniProt: Q92777 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92777 NP_598328 582 62847 T505 P Q R P G G P T T H G D A P S
Chimpanzee Pan troglodytes XP_001171832 699 75941 T622 P Q R P G G P T T H G D A P S
Rhesus Macaque Macaca mulatta XP_001086745 582 63133 T505 P Q R P G G P T T H G D A P S
Dog Lupus familis XP_541766 652 70650 S583 T H G D A P S S S S S L A E A
Cat Felis silvestris
Mouse Mus musculus Q64332 586 63354 T509 Q R P G G P T T T H G D A S S
Rat Rattus norvegicus Q63537 586 63438 S509 Q R P G G P T S T Q V N A S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510384 582 63180 P485 P Q R S P G S P Q Q S R A A S
Chicken Gallus gallus
Frog Xenopus laevis NP_001079204 580 63774 P494 S P Q L P P R P A S G T P P S
Zebra Danio Brachydanio rerio NP_001002597 463 51072 M396 D Q Q L I A D M V I A K M N H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24546 1025 107509 S509 I G R L S S R S S I S E V P E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.8 97.7 82.5 N.A. 93.6 93 N.A. 58.5 N.A. 61.1 53.2 N.A. 26.8 N.A. N.A. N.A.
Protein Similarity: 100 80.8 97.7 84.5 N.A. 95.5 95 N.A. 71.1 N.A. 72.6 66.8 N.A. 37.9 N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 53.3 26.6 N.A. 40 N.A. 20 6.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 60 46.6 N.A. 40 N.A. 26.6 13.3 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 10 0 0 10 0 10 0 70 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 0 0 10 0 0 0 0 40 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 20 50 40 0 0 0 0 50 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 40 0 0 0 0 10 % H
% Ile: 10 0 0 0 10 0 0 0 0 20 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 0 0 30 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % N
% Pro: 40 10 20 30 20 40 30 20 0 0 0 0 10 50 0 % P
% Gln: 20 50 20 0 0 0 0 0 10 20 0 0 0 0 0 % Q
% Arg: 0 20 50 0 0 0 20 0 0 0 0 10 0 0 0 % R
% Ser: 10 0 0 10 10 10 20 30 20 20 30 0 0 20 70 % S
% Thr: 10 0 0 0 0 0 20 40 50 0 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 10 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _